The fluorescence spectra of pharmaceutical compounds under two-photon excitation

被引：0
|
作者：
Agaltsov, AM
Dzhuraev, DR
Gorelik, VS
Rakhmatullaev, IA
机构：
[1] P. N. Lebedev Physical Institute, Russian Academy of Sciences, Moscow 117924
来源：
JOURNAL OF RUSSIAN LASER RESEARCH | 1996年 / 17卷 / 03期
关键词：
D O I：
10.1007/BF02066545
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
Spectra of two-photon-excited fluorescence in pharmaceutical crystalline compounds were obtained and studied as functions of the pump power and delay time. Stimulated fluorescence was observed in polycrystalline Novocaine under high-power pumping. The spectra of two-photon-excited fluorescence in pharmaceutical compounds are localized within the wavelength range of 270-480 nm. The most intense fluorescence wire observed in the Novocaine polycrystals. The therapeutic effect of diphenylhydramine and sulfanilamide is attributed to the fact that the energy of optical quanta of the fluorescence emission in these substances is higher than the energy of excited pi-electrons in tryptophan and nucleotides. The data obtained for the spectra of the pharmaceutical substances studied can be used to solve analytical problems related to identification of the composition and properties of composite pharmaceutical substances.
引用
收藏
页码：305 / 312
页数：8
相关论文
共 50 条
  • [1] The excitation spectra of two-photon induced fluorescence in xanthene dyes
    Wakebe, T
    Van Keuren, E
    JAPANESE JOURNAL OF APPLIED PHYSICS PART 1-REGULAR PAPERS BRIEF COMMUNICATIONS & REVIEW PAPERS, 1999, 38 (6A): : 3556 - 3561
  • [2] Spectra and lifetimes of fluorescence resonance energy transfer fluorophores under two-photon excitation
    Ashman, R
    Crimeen-Irwin, B
    Ludford-Menting, M
    Russell, S
    Gu, M
    SCANNING, 2003, 25 (03) : 116 - 120
  • [3] Two-photon fluorescence excitation and optoacoustic spectra of polyDCHD-HS
    Moroni, L
    Salvi, PR
    Gellini, C
    Dellepiane, G
    Comoretto, D
    Cuniberti, C
    GNSR 2001: STATE OF ART AND FUTURE DEVELOPMENT IN RAMAN SPECTROSCOPY AND RELATED TECHNIQUES, 2002, : 264 - 270
  • [4] Two-photon excitation fluorescence bioassays
    Hanninen, Pekka
    Soukka, Jori
    Soini, Juhani T.
    FLUORESCENCE METHODS AND APPLICATIONS: SPECTROSCOPY, IMAGING, AND PROBES, 2008, 1130 : 320 - 326
  • [5] Two-photon excitation fluorescence microscopy
    So, PTC
    Dong, CY
    Masters, BR
    Berland, KM
    ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, 2000, 2 : 399 - 429
  • [6] Two-color two-photon excitation of fluorescence
    Lakowicz, JR
    Gryczynski, I
    Malak, H
    Gryczynski, Z
    ADVANCES IN FLUORESCENCE SENSING TECHNOLOGY III, 1997, 2980 : 368 - 380
  • [7] Two-color two-photon excitation of fluorescence
    Lakowicz, JR
    Gryczynski, I
    Malak, H
    Gryczynski, Z
    PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1996, 64 (04) : 632 - 635
  • [8] Chromatic two-photon excitation fluorescence imaging
    Xu, Q.
    Shi, K.
    Yin, S.
    Liu, Z.
    JOURNAL OF MICROSCOPY, 2009, 235 (01) : 79 - 83
  • [9] Two-photon excitation in fluorescence lifetime imaging
    Gerritsen, HC
    Vroom, J
    Sytsma, J
    FLUORESCENCE MICROSCOPY AND FLUORESCENT PROBES, VOL 2, 1998, : 55 - 62
  • [10] Two-photon fluorescence excitation in detection of biomolecules
    Soini, E
    Meltola, NJ
    Soini, AE
    Soukka, J
    Soini, JT
    Hänninen, PE
    BIOCHEMICAL SOCIETY TRANSACTIONS, 2000, 28 : 70 - 74
12345