ANTIOXIDANT ACTIVITIES OF HYPERICUM FURSEI L.

In this study, antioxidant activities of H. fursei were investigated. Different model were used for assay. IC50 for DPPH radical-scavenging activity was 7.5 +/- 1.2 mu g ml(-1). The IC50 value for BHA was 92.9 +/- 4.5 mu g ml(-1). The extract showed very good reducing power that was comparable with vitamin C (p>0.05) but showed weak nitric oxide scavenging activity and Fe2+ chelating ability. Extract showed good activity in scavenging of H2O2. Inhibition was 99.1% at 800 mu g ml(-1). The IC50 values for extract and BHA were 333.1 +/- 14.7 and 52.0 +/- 4.5 mu g ml(-1), respectively. Total phenol compounds, by the Folin Ciocalteu method, was 274 +/- 9.6 mg gallic acid equivalent/g of extract and the total flavonoid content, by AlCl3 method was 23.9 +/- 1.4 mg quercetin equivalent/g of extract. Antioxidant activity may be attributed to the presence of phenols and flavonoids in the extract.