A randomized, double-blinded, placebo-controlled, multi-institutional, cross-over, phase II. 5 study of saracatinib (AZD0530), a selective Src kinase inhibitor, in patients with recurrent osteosarcoma localized to the lung.

被引：0

作者：

Baird, Kristin

Reinke, Denise K.

Pressey, Joseph Gerald

Mascarenhas, Leo

Federman, Noah

Marina, Neyssa

Chawla, Sant P.

Lagmay, Joanne Pigues

Goldberg, John M.

Milhem, Mohammed M.

Loeb, David Mark

Butrynski, James E.

Janeway, Katherine A.

Turpin, Brian

Staddon, Arthur P.

Spunt, Sheri L.

Rodler, Eve T.

Schuetze, Scott

Okuno, Scott H.

Heiman, Lee J.

机构：

[1] NCI, Bethesda, MD 20892 USA

[2] Sarcoma Alliance Res Collaborat, Ann Arbor, MI USA

[3] Univ Alabama Birmingham, Birmingham, AL USA

[4] Childrens Hosp Los Angeles, Los Angeles, CA 90027 USA

[5] Univ Calif Los Angeles, Dept Pediat, Los Angeles, CA 90024 USA

[6] Stanford Univ, Sch Med, Palo Alto, CA 94304 USA

[7] Sarcoma Oncol Ctr, Santa Monica, CA USA

[8] Nationwide Childrens Hosp, Gainesville, FL USA

[9] Univ Miami, Miller Sch Med, Miami, FL 33136 USA

[10] Univ Iowa Hosp & Clin, Iowa City, IA 52242 USA

[11] Johns Hopkins Univ, Baltimore, MD USA

[12] Dana Farber Canc Inst, Boston, MA 02115 USA

[13] Cincinnati Childrens Hosp Med Ctr, Cincinnati, OH 45229 USA

[14] Univ Penn, Philadelphia, PA 19104 USA

[15] St Jude Childrens Res Hosp, Memphis, TN 38105 USA

[16] Seattle Canc Care Alliance, Seattle, WA USA

[17] Univ Michigan, Ann Arbor, MI 48109 USA

[18] Mayo Clin, Rochester, MN USA

[19] NCI, Ctr Canc Res, Bethesda, MD 20892 USA

来源：

JOURNAL OF CLINICAL ONCOLOGY | 2013年 / 31卷 / 15期

关键词：

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

TPS10591

引用

页数：1

共 16 条

[1] Effects of the Src Kinase Inhibitor Saracatinib (AZD0530) on Bone Turnover in Healthy Men: A Randomized, Double-Blind, Placebo-Controlled, Multiple-Ascending-Dose Phase I Trial
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[2] A single-centre, placebo-controlled, double-blinded, randomized, cross-over study of Iloprost in patients with Eisenmenger syndrome
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Wort, Stephen J.
EUROPEAN RESPIRATORY JOURNAL, 2018, 52
[3] Effects of the Src kinase inhibitor saracatinib (AZD0530) on bone turnover in healthy men: A randomized, double-blind, placebo-controlled, multiple-ascending-dose phase I trial (vol 25, pg 463, 2010)
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Clack, Glen
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[10] Efficacy of oral administration of cystine and theanine in colorectal cancer patients undergoing capecitabine-based adjuvant chemotherapy after surgery: a multi-institutional, randomized, double-blinded, placebo-controlled, phase II trial (JORTC-CAM03)
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