The Effect of Immune-Related Genes on Colonic Adenocarcinoma Prognosis

被引：0
|
作者：
Hou, Mingyu [1 ]
Ma, Jiakang [1 ]
Lin, Xiaoyan [1 ]
Ma, Jun [2 ]
机构：
[1] Zhengzhou Univ, Affiliated Hosp 2, Dept Oncol, Zhengzhou 450000, Henan, Peoples R China
[2] Zhengzhou Univ, Inst Digest Dis, Zhengzhou 450000, Henan, Peoples R China
来源：
NANOSCIENCE AND NANOTECHNOLOGY LETTERS | 2020年 / 12卷 / 09期
关键词：
Immune-Related Genes; Colonic Adenocarcinomas; Prognosis; TCGA Database; Immune; COLORECTAL ADENOCARCINOMA; CANCER;
D O I：
10.1166/nnl.2020.3209
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Colorectal adenocarcinoma (COAD) is the most common type of colon cancer, and its occurrence is intimately associated with immune-related gene (IRG) expression. In this research, the IRG expression was analyzed and 484 were found significantly different between COAD and normal tissue. To construct a COAD patient IRGs-prognosis model, 11 of the IRGs were selected by multivariate Cox analysis. IRGs in the model were closely related to tumor invasion depth, lymphoid involvement, distant metastasis, stage, and age. This work lays the foundation for future scientific research and clinical work related to COAD.
引用
收藏
页码：1055 / 1062
页数：8
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