The work on deoxyribonucleic acid (DNA) computers has attracted the attention of many researchers because of its faster speed, low energy consumption and compact size. However, the revolutionary development for New Age computing paradigms does not mean the end of popular silicon-based microelectronics since this new technology is still in its theoretical stage. When it reaches its implementation stage, microelectronics are still needed for the numerical simulation of new computing devices, technology-development processes and for higher level system studies. In the next few years, new computing paradigm combinations with existing microelectronics and hybrid system demonstrations are the major challenge for researchers.