Using CRISPR/Cas9-Based Epigenetic Editing to Study the Role of Schizophrenia-Related Alterations in DNA Methylation on Dendritic Spine Density

被引：0
|
作者：
Kuflewski, Jennifer [1 ]
Hensler, Christopher [2 ]
Tariq, Shahwar [2 ]
Lewis, David [2 ]
Sweet, Robert [2 ]
McKinney, Brandon [2 ]
机构：
[1] Univ Pittsburgh, Med Ctr, Western Psychiat Inst & Clin, Pittsburgh, PA 15260 USA
[2] Univ Pittsburgh, Pittsburgh, PA 15260 USA
来源：
BIOLOGICAL PSYCHIATRY | 2019年 / 85卷 / 10期
关键词：
Schizophrenia; DNA methylation; Epigenetics; Human Postmortem Brain; Dendritic Spine;
D O I：
10.1016/j.biopsych.2019.03.702
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
F165
引用
收藏
页码：S277 / S277
页数：1
相关论文
共 34 条
  • [1] Using a CRISPR/Cas9-Based Epigenetic Editing Tool to Study the Cell-Type-Specific Effects of the DNA Methylation Alterations Observed in the Auditory Cortex Subjects With Schizophrenia
    McKinney, Brandon
    Hensler, Christopher
    Kuflewski, Jennifer
    Wei, Yue
    Ding, Ying
    Lewis, David
    Devlin, Bernie
    Sweet, Robert
    BIOLOGICAL PSYCHIATRY, 2020, 87 (09) : S61 - S61
  • [2] Genome editing using CRISPR/Cas9-based knock-in approaches in zebrafish
    Albadri, Shahad
    Del Bene, Filippo
    Revenu, Celine
    METHODS, 2017, 121 : 77 - 85
  • [3] Reprogrammable CRISPR/Cas9-based system for inducing site-specific DNA methylation
    McDonald, James I.
    Celik, Hamza
    Rois, Lisa E.
    Fishberger, Gregory
    Fowler, Tolison
    Rees, Ryan
    Kramer, Ashley
    Martens, Andrew
    Edwards, John R.
    Challen, Grant A.
    BIOLOGY OPEN, 2016, 5 (06): : 866 - 874
  • [4] Editing DNA Methylation at Dendritic-Spine Associated Locus via CRISPR-dCas9
    Hensler, Christopher
    Salerno, Luca
    Kuflewski, Jennifer
    Sweet, Robert
    McKinney, Brandon
    BIOLOGICAL PSYCHIATRY, 2021, 89 (09) : S118 - S118
  • [5] Editing of DNA methylation using CRISPR/Cas9 and a ssDNA template in human cells
    Katayama, Shota
    Andou, Masao
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2021, 581 : 20 - 24
  • [6] Automated CRISPR/Cas9-based genome editing of human pluripotent stem cells using the StemCellFactory
    Niessing, Bastian
    Breitkreuz, Yannik
    Elanzew, Andreas
    de Toledo, Marcelo A. S.
    Vajs, Peter
    Nolden, Marina
    Erkens, Frederik
    Wanek, Paul
    Yeung, Si Wah Christina Au
    Haupt, Simone
    Koenig, Niels
    Peitz, Michael
    Schmitt, Robert H.
    Zenke, Martin
    Bruestle, Oliver
    FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2024, 12
  • [7] CRISPR/Cas9-Based Gene Editing Using Egg Cell-Specific Promoters in Arabidopsis and Soybean
    Zheng, Na
    Li, Ting
    Dittman, Jaime D.
    Su, Jianbin
    Li, Riqing
    Gassmann, Walter
    Peng, Deliang
    Whitham, Steven A.
    Liu, Shiming
    Yang, Bing
    FRONTIERS IN PLANT SCIENCE, 2020, 11
  • [8] Regulation of gene expression by altered promoter methylation using a CRISPR/Cas9-mediated epigenetic editing system
    Kang, Jeong Gu
    Park, Jin Suk
    Ko, Jeong-Heosn
    Kim, Yong-Sam
    SCIENTIFIC REPORTS, 2019, 9 (1)
  • [9] Regulation of gene expression by altered promoter methylation using a CRISPR/Cas9-mediated epigenetic editing system
    Jeong Gu Kang
    Jin Suk Park
    Jeong-Heosn Ko
    Yong-Sam Kim
    Scientific Reports, 9
  • [10] CRISPR/Cas9-based targeted genome editing for correction of recessive dystrophic epidermolysis bullosa using iPS cells
    Jackow, Joanna
    Guo, Zongyou
    Hansen, Corey
    Abaci, Hasan E.
    Doucet, Yanne S.
    Shin, Jung U.
    Hayashi, Ryota
    DeLorenzo, Dominick
    Kabata, Yudai
    Shinkuma, Satoru
    Salas-Alanis, Julio C.
    Christiano, Angela M.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 116 (52) : 26846 - 26852
1234