Synthesis and Characterization of New Diketone Analogues of Podophyllotoxin

被引：3
|
作者：
Hemakumar, K. H. [1 ]
Sathisha, A. D. [1 ]
Basavaraju, Y. B. [1 ]
机构：
[1] Univ Mysore, Dept Studies Chem, Mysore 570006, Karnataka, India
来源：
E-JOURNAL OF CHEMISTRY | 2008年 / 5卷 / 01期
关键词：
Benzophenones; Stobbe condensation; Itaconic acids; Sodium-amalgam; Benzhydryl succinic acids; Diketones;
D O I：
10.1155/2008/314724
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The new compounds 6,6a-dihydro-2,3-dimethoxy-9-nitro-11bH benzo [C]-fluoren 5,7-dione, 6,6a-dihydro-2,3-dimethoxy-9-chloro-11bH benzo[C]-fluoren-5,7-dione and 6,6a-dihydro-2,3-dimethoxy-9-fluoro-11bH benzo[C]-fluoren-5,7-dione were synthesized in high yields. They are analogues of naturally occurring lignan podophyllotoxin which exhibits anticancer activity. They are very essential to study anticancer activity.
引用
收藏
页码：114 / 119
页数：6
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