Tumor Microenvironment and Immunotherapy: The Whole Picture Is Better Than a Glimpse

被引：44
|
作者：
Church, Sarah E. [1 ,2 ,3 ]
Galon, Jerome [1 ,2 ,3 ]
机构：
[1] INSERM, UMRS1138, Lab Integrat Canc Immunol, F-75006 Paris, France
[2] Univ Paris 05, F-75006 Paris, France
[3] Univ Paris 06, Cordeliers Res Ctr, F-75006 Paris, France
来源：
IMMUNITY | 2015年 / 43卷 / 04期
关键词：
IMMUNE CELLS; CANCER;
D O I：
10.1016/j.immuni.2015.10.004
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Predicting cancer patients' response to therapy is essential for curing disease and improving quality of life. Garraway and colleagues demonstrate that the frequency and number of neoantigens, non-synonymous mutations, and adaptive immune genes, but not the assessment of individual recurrent neoantigens or mutations, predicts patient responses to immunotherapy.
引用
收藏
页码：631 / 633
页数：4
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