Saniculoside N from Sanicula europaea L.

被引:29
|
作者
Arda, N
Goren, N
Kuru, A
Pengsuparp, T
Pezzuto, JM
Qiu, SX
Cordell, GA
机构
[1] TUBITAK,MARMARA RES CTR,MAT & CHEM TECHNOL RES INST,DEPT CHEM,TR-41470 GEBZE,TURKEY
[2] UNIV ILLINOIS,COLL PHARM,DEPT MED CHEM & PHARMACOGNOSY,PROGRAM COLLABORAT RES PHARMACEUT SCI,CHICAGO,IL 60612
来源
JOURNAL OF NATURAL PRODUCTS | 1997年 / 60卷 / 11期
关键词
D O I
10.1021/np9701790
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Extracts from the aerial parts of Sanicula europaea L. were investigated for their anti-HN activity, and the 50% ethanolic extract was shown to exhibit the highest activity. A new triterpene saponin glycoside, 21 beta-(angeloyloxy)-3-O-[beta-D-arabinopyranosyl(1-->4)-beta-D-glucopyranosyl(1-->3)-beta-D-glucuronopyranosyl propyl ester]-3 beta,15,16,22 alpha,28 beta-pentahydroxy-Delta(12)-oleanene, saniculoside N (1), in addition to the known phenolic acids, rosmarinic acid (2), and caffeic acid(3) were isolated as major components. Rosmarinic acid was established as the principal active substance.
引用
收藏
页码:1170 / 1173
页数:4
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