Malignant fibrous histiocytoma secondary to fibrous dysplasia - A case report

A mart of 50 years of age had a malignant fibrous histiocytoma secondary to asymptomatic fibrous dysplasia of the proximal femur. Radiographs showed ill-defined osteolytic changes near to the fibrous lesion which had a ground glass appearance, The histology was of a malignant fibrous histiocytoma concomitant with fibrous dysplasia. Art extensive resection of the tumour was carried out and chemotherapy given, but the patient died from a liver metastasis 9 months later. The possibility of malignancy should be considered if a patient with fibrous dysplasia has any progressive symptoms.