Synthesis of Coumarino[4,3-b]pyran-4-one Derivatives

被引：3

作者：

Wang, Daolin ^{[1
]}

Yang, Feifei ^{[1
]}

Liu, Zhong ^{[2
]}

Dong, Zhe ^{[1
]}

Zhao, Wei ^{[1
]}

机构：

[1] Bohai Univ, Key Lab Synth & Applicat Funct Compound, Coll Chem Chem Engn & Food Safety, Jinzhou 121003, Peoples R China

[2] Jilin Res Inst Petrochem Technol, Changchun 130021, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2014年 / 34卷 / 01期

关键词：

coumarin; 3-cinnamoyl-4-hydroxycoumarins; coumarino[4,3-b]pyran-4-one; iodine; synthesis; ANTIBACTERIAL ACTIVITY; IODINE; COUMARIN;

D O I：

10.6023/cjoc201307047

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient and easy method for the synthesis of coumarino[4,3-b]pyran-4-one derivatives underwent oxidative cyclization of 3-cinnamoyl-4-hydroxycoumarins, synthesized from condensation between 3-acetyl-4-hydroxycoumarin and aromatic aldehydes in the presence of piperidine and PEG-400 by using iodine in DMSO, has been described. All of above compounds have been confirmed by NMR, JR. MS spectra and elemental analysis.

引用

页码：204 / 209

页数：6

共 26 条

[1] Synthesis and Photooxygenation of Furo[3,2-c]coumarin Derivatives as Antibacterial and DNA Intercalating Agent
Al-Sehemi, Abdullah G.
El-Gogary, Sameh R.
[J]. CHINESE JOURNAL OF CHEMISTRY, 2012, 30 (02) : 316 - 320
[2] A Simple Synthesis of Functionalized 3-Bromocoumarins by a One-Pot Three-Component Reaction
Audisio, Davide
Messaoudi, Samir
Brion, Jean-Daniel
Alami, Mouad
[J]. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2010, 2010 (06) : 1046 - 1051
[3] Synthesis and Antitumor Activity of Novel Coumarin Derivatives via a Three-component Reaction in Water
Chen, Zhiwei
Bi, Jianhao
Su, Weike
[J]. CHINESE JOURNAL OF CHEMISTRY, 2013, 31 (04) : 507 - 514
[4] Denish C., 2012, Asian, V2, P126
[5] Geen G.R., 1996, Comprehensive heterocyclic chemistry II, V5, P469, DOI DOI 10.1016/B978-008096518-5.00112-X
[6] A rapid access to new coumarinyl chalcone and substituted chromeno[4,3-c]pyrazol-4(1H)-ones and their antibacterial and DPPH radical scavenging activities
Hamdi, Naceur
Fischmeister, Cedric
Carmen Puerta, M.
Valerga, Pedro
[J]. MEDICINAL CHEMISTRY RESEARCH, 2011, 20 (04) : 522 - 530
[7] Expedious synthesis for α, β-unsaturated coumarin derivatives using boran chelates: A novel class of potential antibacterial and antioxidant agents
Hamdi, Naceur
Bouabdallah, Feten
Romerosa, Antonio
Benhassen, Rached
[J]. COMPTES RENDUS CHIMIE, 2010, 13 (10) : 1261 - 1268
[8] Quercetin and Its Derivatives: Synthesis, Pharmacological Uses with Special Emphasis on Anti-Tumor Properties and Prodrug with Enhanced Bio-Availability
Hirpara, Ketan V.
Aggarwal, Pawan
Mukherjee, Amrita J.
Joshi, Narendra
Burman, Anand C.
[J]. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2009, 9 (02) : 138 - 161
[9] The combinatorial synthesis of bicyclic privileged structures or privileged substructures
Horton, DA
Bourne, GT
Smythe, ML
[J]. CHEMICAL REVIEWS, 2003, 103 (03) : 893 - 930
[10] Design and Synthesis of α-Cyclodextrin Modified Coumarin
Jiang Jinqiang
Chen Xin
Yin Ming
Wang Zhouping
Liu Xiaoya
Chen Mingqing
[J]. ACTA CHIMICA SINICA, 2012, 70 (05) : 525 - 529

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