Molecular Epidemiology of Vancomycin-Resistant Enterococcus faecium Infecting Recipients of Solid Organs in the Transplant Surgery Ward in 2005 and 2006

被引:3
|
作者
Mlynarczyk, A. [1 ,4 ]
Grzybowska, W. [1 ]
Mrowka, A.
Tyski, S. [1 ,5 ]
Buczkowska, T. [6 ]
Pazik, J. [6 ]
Durlik, M. [6 ]
Kwiatkowski, A. [3 ]
Adadynski, L. [3 ]
Chmura, A. [3 ]
Paczek, L. [2 ]
Mlynarczyk, G. [4 ]
机构
[1] Natl Med Inst, Dept Antibiot & Microbiol, Warsaw, Poland
[2] Med Univ Warsaw, Inst Transplantat, Dept Immunol Transplantol & Internal Dis, Warsaw, Poland
[3] Med Univ Warsaw, Dept Gen & Transplantat Surg, Warsaw, Poland
[4] Natl Med Inst, Dept Med Microbiol, Warsaw, Poland
[5] Natl Med Inst, Dept Pharmaceut Microbiol, Warsaw, Poland
[6] Natl Med Inst, Dept Transplant Med & Nephrol, Warsaw, Poland
关键词
STRAIN;
D O I
10.1016/j.transproceed.2009.08.012
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Background. The aim of the investigations was to compare the vancomycin-resistant Enterococcus faecium (VREfm) strains obtained from our patients. Materials and Methods. Strains were compared using restriction fragment length polymorphism-pulsed field gel electrophoresis (RFLP-PFGE) of bacterial DNA. Results. VREfm infected 26 liver recipients, 22 kidney recipients, and 9 other surgery or nephrology patients. Only five strains possessed the vanB determinant. The PFGE analysis revealed two large and several small groups of related strains. Conclusions. The PFGE analysis enabled the investigation of VRE epidemiology among patients after transplantation. Strains with similar patterns most probably originated from one source and clearly suggested an outbreak.
引用
收藏
页码:3261 / 3263
页数:3
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