prion disease;
dementia;
magnetic resonance imaging;
diffusion-weighted sequence;
D O I:
10.1590/S0004-282X2002000600003
中图分类号:
Q189 [神经科学];
学科分类号:
071006 ;
摘要:
Creutzfeldt-Jakob disease (CJD) is a progressive and fatal dementing illness caused by a virus like agent called prion. Currently, the definitive diagnosis can only be made through brain biopsy. Given its potential transmissibility, it is paramount to have noninvasive and reliable means to detect the disease. The present case reports on a 63 year-old man with biopsy proven CID, and evaluates the dependability of diffusion-weighted MRI in this condition, stressing the importance of this particular sequence to its diagnosis.
机构:
Univ Foggia, Dept Med & Surg Sci, Via Luigi Pinto 1, I-71100 Foggia, ItalyUniv Foggia, Dept Med & Surg Sci, Via Luigi Pinto 1, I-71100 Foggia, Italy
Carapelle, Elena
Di Francescantonio, Valeria
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机构:
Univ Foggia, Dept Med & Surg Sci, Via Luigi Pinto 1, I-71100 Foggia, ItalyUniv Foggia, Dept Med & Surg Sci, Via Luigi Pinto 1, I-71100 Foggia, Italy
Di Francescantonio, Valeria
Bertozzi, Vincenzo
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机构:
Riuniti Hosp, Dept Radiol, Foggia, ItalyUniv Foggia, Dept Med & Surg Sci, Via Luigi Pinto 1, I-71100 Foggia, Italy
Bertozzi, Vincenzo
Perfetto, Francesco
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机构:
Riuniti Hosp, Dept Radiol, Foggia, ItalyUniv Foggia, Dept Med & Surg Sci, Via Luigi Pinto 1, I-71100 Foggia, Italy
Perfetto, Francesco
Lacanna, Antonio
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机构:
Riuniti Hosp, Dept Radiol, Foggia, ItalyUniv Foggia, Dept Med & Surg Sci, Via Luigi Pinto 1, I-71100 Foggia, Italy
Lacanna, Antonio
Mundi, Ciro
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机构:
United Hosp Foggia, Dept Neurosci, Foggia, ItalyUniv Foggia, Dept Med & Surg Sci, Via Luigi Pinto 1, I-71100 Foggia, Italy
Mundi, Ciro
Avolio, Carlo
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机构:
Univ Foggia, Dept Med & Surg Sci, Via Luigi Pinto 1, I-71100 Foggia, ItalyUniv Foggia, Dept Med & Surg Sci, Via Luigi Pinto 1, I-71100 Foggia, Italy
Avolio, Carlo
Grilli, Giampaolo
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机构:
Riuniti Hosp, Dept Radiol, Foggia, ItalyUniv Foggia, Dept Med & Surg Sci, Via Luigi Pinto 1, I-71100 Foggia, Italy
机构:
Peoples Liberat Army Gen Hosp, Dept Radiol, Beijing 100853, Peoples R ChinaPeoples Liberat Army Gen Hosp, Dept Radiol, Beijing 100853, Peoples R China
Lou Xin
Ma Lin
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机构:
Peoples Liberat Army Gen Hosp, Dept Radiol, Beijing 100853, Peoples R ChinaPeoples Liberat Army Gen Hosp, Dept Radiol, Beijing 100853, Peoples R China
Ma Lin
An Ning-Yu
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机构:
Peoples Liberat Army Gen Hosp, Dept Radiol, Beijing 100853, Peoples R ChinaPeoples Liberat Army Gen Hosp, Dept Radiol, Beijing 100853, Peoples R China
An Ning-Yu
Cai You-Quan
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机构:
Peoples Liberat Army Gen Hosp, Dept Radiol, Beijing 100853, Peoples R ChinaPeoples Liberat Army Gen Hosp, Dept Radiol, Beijing 100853, Peoples R China
Cai You-Quan
Liang Yan
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机构:
Peoples Liberat Army Gen Hosp, Dept Radiol, Beijing 100853, Peoples R ChinaPeoples Liberat Army Gen Hosp, Dept Radiol, Beijing 100853, Peoples R China
Liang Yan
Guo Xing-gao
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机构:
Peoples Liberat Army Gen Hosp, Dept Radiol, Beijing 100853, Peoples R ChinaPeoples Liberat Army Gen Hosp, Dept Radiol, Beijing 100853, Peoples R China