Application of Molecularly Imprinted Polymer-modified Potentiometric Sensor for Quantitative Determination of Histamine in Serum

被引：3
|
作者：
Konishi, Atsuko [1 ]
Takegami, Shigehiko [1 ]
Idosaki, Yoko [1 ]
Kitade, Tatsuya [1 ]
机构：
[1] Kyoto Pharmaceut Univ, Dept Analyt Chem, Yamashina Ku, 5 Misasaginakauchi Cho, Kyoto 6078414, Japan
来源：
ANALYTICAL SCIENCES | 2020年 / 36卷 / 12期
关键词：
Potentiometric sensor; molecularly imprinted polymer; histamine; serum; quantitative determination; selectivity; H-4; RECEPTOR;
D O I：
10.2116/analsci.20N018
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A molecularly imprinted polymer-modified potentiometric histamine (HIS) sensor was prepared and used for quantitative determination of HIS in bovine serum. The calibration curve using the potential responses measured in 1 x 10(-3) mol L-1 phosphate buffer (pH 7.4) showed good linearity in the HIS concentration range of 3 x 10(-4) to 1 x 10(-2) mol L-1 (r = 0.92), with a detection limit of 1.6 x 10(-4) mol L-1. In bovine serum samples, the HIS sensor showed good recovery values of 91 - 104%. Therefore, this HIS sensor successfully determined the HIS concentration in bovine serum samples.
引用
收藏
页码：1561 / 1563
页数：3
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