Interpreting Alzheimer disease polygenic scores

被引：5
|
作者：
Tan, Chin Hong [1 ]
Desikan, Rahul S. [1 ,2 ]
机构：
[1] Univ Calif San Francisco, Neuroradiol Sect, Dept Radiol & Biomed Imaging, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, Dept Neurol, San Francisco, CA USA
来源：
ANNALS OF NEUROLOGY | 2018年 / 83卷 / 03期
关键词：
RISK PREDICTION; ASSOCIATION; PREVENTION; LOCI;
D O I：
10.1002/ana.25164
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
引用
收藏
页码：443 / 445
页数：3
相关论文
共 50 条
  • [1] Polygenic risk scores in familial Alzheimer disease
    Tosto, Giuseppe
    Bird, Thomas D.
    Tsuang, Debby
    Bennett, David A.
    Boeve, Bradley F.
    Cruchaga, Carlos
    Faber, Kelley
    Foroud, Tatiana M.
    Farlow, Martin
    Goate, Alison M.
    Bertlesen, Sarah
    Graff-Radford, Neill R.
    Medrano, Martin
    Lantigua, Rafael
    Manly, Jennifer
    Ottman, Ruth
    Rosenberg, Roger
    Schaid, Daniel J.
    Schupf, Nicole
    Stern, Yaakov
    Sweet, Robert A.
    Mayeux, Richard
    NEUROLOGY, 2017, 88 (12) : 1180 - 1186
  • [2] Polygenic Hazard Scores in Preclinical Alzheimer Disease
    Tan, Chin Hong
    Hyman, Bradley T.
    Tan, Jacinth J. X.
    Hess, Christopher P.
    Dillon, William P.
    Schellenberg, Gerard D.
    Besser, Lilah M.
    Kukull, Walter A.
    Kauppi, Karolina
    McEvoy, Linda K.
    Andreassen, Ole A.
    Dale, Anders M.
    Fan, Chun Chieh
    Desikan, Rahul S.
    ANNALS OF NEUROLOGY, 2017, 82 (03) : 484 - 488
  • [3] Polygenic Risk Scores in Familial Alzheimer's Disease
    Tosto, Giuseppe
    Bird, Thomas D.
    Bennet, David A.
    Boeve, Bradley F.
    Brickman, Adam M.
    Cruchaga, Carlos
    Faber, Kelley
    Foroud, Tatiana M.
    Farlow, Martin
    Goate, Alison M.
    Graff-Radford, Neil R.
    Lantigua, Rafael
    Manly, Jennifer
    Ottman, Ruth
    Rosenberg, Roger
    Schaid, Daniel J.
    Schupf, Nicole
    Stern, Yaakov
    Sweet, Robert A.
    Mayeux, Richard
    ANNALS OF NEUROLOGY, 2016, 80 : S182 - S182
  • [4] Interpreting polygenic scores, polygenic adaptation, and human phenotypic differences
    Rosenberg, Noah A.
    Edge, Michael D.
    Pritchard, Jonathan K.
    Feldman, Marcus W.
    EVOLUTION MEDICINE AND PUBLIC HEALTH, 2019, (01) : 26 - 34
  • [5] Polygenic risk and hazard scores for Alzheimer's disease prediction
    Leonenko, Ganna
    Sims, Rebecca
    Shoai, Maryam
    Frizzati, Aura
    Bossu, Paola
    Spalletta, Gianfranco
    Fox, Nick C.
    Williams, Julie
    Hardy, John
    Escott-Price, Valentina
    Tsolaki, Magda
    Craig, David
    Avramidou, Despoina
    Germanou, Antonia
    Koutroumani, Maria
    Gkatzima, Olymbia
    Hampel, Harald
    Kehoe, Patrick G.
    Love, Seth
    Rubinsztein, David C.
    Frolich, Lutz
    McGuinness, Bernadette
    Johnston, Janet A.
    Passmore, Peter
    Drichel, Dmitriy
    Rossor, Martin
    Schott, Jonathan M.
    Warren, Jason D.
    Bras, Jose
    Guerreiro, Rita
    Kawalia, Amit
    Hughes, Joseph T.
    Patel, Yogen
    Lupton, Michelle K.
    Proitsi, Petra
    Powell, John
    Kauwe, John S. K.
    Mancuso, Michelangelo
    Bonuccelli, Ubaldo
    Uphill, James
    Fisher, Elizabeth
    Masullo, Carlo
    Soininen, Hilkka
    Bisceglio, Gina
    Ma, Li
    Dickson, Dennis W.
    Graff-Radford, Neill R.
    Carrasquillo, Minerva M.
    Younkin, Steven G.
    Sorbi, Sandro
    ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY, 2019, 6 (03): : 456 - 465
  • [6] Polygenic Risk Scores and Epistatic Components for Alzheimer's Disease Prediction
    Sun, Rui
    Xia, Xiaoxuan
    Wang, Maggie H.
    GENETIC EPIDEMIOLOGY, 2019, 43 (07) : 911 - 912
  • [7] Identification of biological pathways to Alzheimer's disease using polygenic scores
    Harrison, J.
    Baker, E.
    Hubbard, L.
    Linden, D.
    Williams, J.
    Escott-Price, V.
    Holmans, P.
    EUROPEAN PSYCHIATRY, 2017, 41 : S166 - S167
  • [8] Improving the Utility of Polygenic Risk Scores as a Biomarker for Alzheimer's Disease
    Vlachakis, Dimitrios
    Papakonstantinou, Eleni
    Sagar, Ram
    Bacopoulou, Flora
    Exarchos, Themis
    Kourouthanassis, Panos
    Karyotis, Vasileios
    Vlamos, Panayiotis
    Lyketsos, Constantine
    Avramopoulos, Dimitrios
    Mahairaki, Vasiliki
    CELLS, 2021, 10 (07)
  • [9] Mitochondrial pathway polygenic risk scores are associated with Alzheimer's Disease
    Paliwal, Devashi
    McInerney, Tim W.
    Pa, Judy
    Swerdlow, Russell H.
    Easteal, Simon
    Andrews, Shea J.
    NEUROBIOLOGY OF AGING, 2021, 108 : 213 - 222
  • [10] Polygenic resilience scores capture protective genetic effects for Alzheimer's disease
    Hou, Jiahui
    Hess, Jonathan L.
    Armstrong, Nicola
    Bis, Joshua C.
    Grenier-Boley, Benjamin
    Karlsson, Ida K.
    Leonenko, Ganna
    Numbers, Katya
    O'Brien, Eleanor K.
    Shadrin, Alexey
    Thalamuthu, Anbupalam
    Yang, Qiong
    Andreassen, Ole A.
    Brodaty, Henry
    Gatz, Margaret
    Kochan, Nicole A.
    Lambert, Jean-Charles
    Laws, Simon M.
    Masters, Colin L.
    Mather, Karen A.
    Pedersen, Nancy L.
    Posthuma, Danielle
    Sachdev, Perminder S.
    Williams, Julie
    Fan, Chun Chieh
    Faraone, Stephen V.
    Fennema-Notestine, Christine
    Lin, Shu-Ju
    Escott-Price, Valentina
    Holmans, Peter
    Seshadri, Sudha
    Tsuang, Ming T.
    Kremen, William S.
    Glatt, Stephen J.
    TRANSLATIONAL PSYCHIATRY, 2022, 12 (01)
12345