Drug-related cardiac pathology

被引:19
|
作者
Butany, J. [1 ,2 ]
Ahn, E. [1 ]
Luk, A. [3 ]
机构
[1] Toronto Gen Hosp, Dept Pathol, Univ Hlth Network, Toronto, ON M5G 2C4, Canada
[2] Univ Toronto, Fac Med, Dept Lab Med & Pathobiol, Toronto, ON, Canada
[3] Univ Toronto, Dept Med, Toronto, ON, Canada
关键词
TORSADE-DE-POINTES; DOSE CYCLOPHOSPHAMIDE THERAPY; QT INTERVAL PROLONGATION; BREAST-CANCER; HYPERSENSITIVITY MYOCARDITIS; CARDIOVASCULAR TOXICITY; INDUCED CARDIOMYOPATHY; INDUCED CARDIOTOXICITY; ANTIPSYCHOTIC-DRUGS; METHAMPHETAMINE USE;
D O I
10.1136/jcp.2008.058255
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Many commonly used drugs, with each causing changes that may be potentially lethal, can adversely affect the function of the heart. In addition some drugs have synergistic effects that can also damage cardiovascular tissues. The drug-related cardiotoxic effects of antineoplastic agents, psychotropic medications, heavy metals, substances of abuse, promotility agents, antihistamines, antimicrobials and antiarrhythmic agents are discussed. Hypersensitivity myocarditis is also discussed.
引用
收藏
页码:1074 / 1084
页数:11
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