Conformational landscape of the protein kinase A Inhibitor PKI studied by fluorescence and NMR spectroscopy

被引：0
|
作者：
Olivieri, Cristina [1 ]
Li, Geoffrey [2 ]
Kim, Jonggul [1 ]
Porcelli, Fernando [3 ]
Neibergall, Matthew [4 ]
Muretta, Joseph M. [1 ]
Thomas, David D. [1 ]
Taylor, Susan S. [5 ,6 ]
Gianluigi, Veglia [1 ]
机构：
[1] Univ Minnesota, Dept Biochem Mol Biol & Biophys, Minneapolis, MN USA
[2] Univ Minnesota, Dept Chem, 207 Pleasant St SE, Minneapolis, MN 55455 USA
[3] Univ Tuscia, Dept Innovat Biol Agrofood & Forest Syst, Viterbo, Italy
[4] Bethel Coll, Chemitry, St Paul, MN USA
[5] Univ Calif San Diego, Dept Pharmacol, San Diego, CA 92103 USA
[6] Univ Calif San Diego, Dept Chem & Biochem, San Diego, CA 92103 USA
来源：
FASEB JOURNAL | 2017年 / 31卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
913.16
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Elucidating the Mechanism of Recognition and Binding of Protein Kinase Inhibitor by Protein Kinase a using NMR and Fluorescence Spectroscopy
    Li, Geoffrey
    Olivieri, Cristina
    Neibergall, Matthew
    Kim, Jonggul
    Taylor, Susan
    Muretta, Joseph
    Veglia, Gianluigi
    BIOPHYSICAL JOURNAL, 2016, 110 (03) : 558A - 558A
  • [2] The conformational landscape of 5-methoxytryptamine studied by rotationally resolved fluorescence spectroscopy and resonant ionization spectroscopy
    Vu, Thi Bao Chau
    Kalkman, Ivo
    Meerts, W. Leo
    Brand, Christian
    Svartsov, Yuriy N.
    Wiedemann, Sascha
    Weinkauf, Rainer
    Schmitt, Michael
    PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2009, 11 (14) : 2433 - 2440
  • [3] Assignment of the HN-HSQC NMR spectrum of heat stable protein kinase inhibitor (PKI)
    Stultz, Benjamin
    Kim, Jonggul
    Veglia, Gianluigi
    Neibergall, Matthew
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 249
  • [4] Conformational Plasticity in Tyrosine Kinase Inhibitor-Kinase Interactions Revealed with Fluorescence Spectroscopy and Theoretical Calculations
    Khattab, Muhammad
    Wang, Feng
    Clayton, Andrew H. A.
    JOURNAL OF PHYSICAL CHEMISTRY B, 2018, 122 (17): : 4667 - 4679
  • [5] Conformational change dynamics of DNA and protein studied by single-molecule fluorescence spectroscopy
    Choi, Jungkweon
    Majima, Tetsuro
    Kobunshi, 2011, 60 (02) : 70 - 73
  • [6] The role of NMR spectroscopy in mapping the conformational landscape of GPCRs
    Bostock, Mark J.
    Solt, Andras S.
    Nietlispach, Daniel
    CURRENT OPINION IN STRUCTURAL BIOLOGY, 2019, 57 : 145 - 156
  • [7] Protein complexes studied by NMR spectroscopy
    Wang, AJ
    Englander, SW
    CURRENT OPINION IN BIOTECHNOLOGY, 1996, 7 (04) : 403 - 408
  • [8] Protein complexes studied by NMR spectroscopy
    Curr Opin Biotechnol, 4 (403):
  • [9] Spectroscopic studies of the intrinsically disordered protein kinase A inhibitor PKI
    Stultz, Benjamin
    Li, Geoffrey
    Olivieri, Cristina
    Veglia, Gianluigi
    Neibergall, Matthew
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 251
  • [10] Endogenous protein kinase A inhibitor (PKIα) modulates synaptic activity
    de Lecea, L
    Criado, JR
    Rivera, S
    Wen, W
    Soriano, E
    Henriksen, SJ
    Taylor, SS
    Gall, CM
    Sutcliffe, JG
    JOURNAL OF NEUROSCIENCE RESEARCH, 1998, 53 (03) : 269 - 278
12345