Langerhans cell histiocytosis of the thyroid

Introduction > Langerhans cell histiocytosis, also known as histiocytosis X, has a broad clinical spectrum and highly variable prognosis. Its localization in the thyroid gland is relatively rare and presents particular diagnostic and therapeutic difficulties. Case > A 38-year-old man consulted for on anterior cervical moss that doted back to childhood but which had grown substantially in volume over the post seven months. The workup indicated a left thyroid nodule. We performed a thyroid lobectomy with isthmusectomy Immunohistochemical and pathology analyses showed Langerhans cell histiocytosis of the thyroid. The immediate postoperative course and subsequent outcome were good (follow-up: 34 months). Conclusion > Diagnosis and treatment of Langerhans cell histiocytosis in the thyroid gland often require multidisciplinary cooperation to analyze clinical, radiological, and pathology findings.