Cnidarian toxins: recent evidences for potential therapeutic uses

被引:0
|
作者
Jayathilake, J. M. N. J. [1 ]
Guanthilake, K. V. K. [1 ]
机构
[1] Univ Sri Jayewardenepura, Dept Zool, Fac Sci Appl, Nugegoda, Sri Lanka
来源
EUROPEAN ZOOLOGICAL JOURNAL | 2020年 / 87卷 / 01期
关键词
Cnidarian toxicity; bioactivities; therapeutic agents; JELLYFISH AURELIA-AURITA; ANTIMICROBIAL ACTIVITY; MOON JELLYFISH; MARINE TOXINS; VENOM; NEMATOCYST; PEPTIDE; PROTEIN;
D O I
10.1080/24750263.2020.1837268
中图分类号
Q95 [动物学];
学科分类号
071002 ;
摘要
Marine toxins have received global attention for their involvement in human intoxication. Many marine phyla are well adapted to produce venoms or toxins protect themselves from associated micro fauna, predators and pathogens. Despite the toxicity, some bio toxins stand as potential drug leads in human and veterinary medicine. Amongst all marine fauna, Cnidarians are well renowned for producing bioactive peptides which are used in drug development, as they harbor various biological activities; anticancer, anti-inflammatory, immunomodulatory, radical scavenging, anti-parasitic activities, etc. Particularly, this review summarizes the bioactivities recorded from Cnidarian toxins and the possibility of using them as therapeutic agents, leading to develop into commercial products in the future.
引用
收藏
页码:708 / 713
页数:6
相关论文
共 50 条
  • [1] Therapeutic Uses of Bacterial Subunit Toxins
    Lingwood, Clifford
    TOXINS, 2021, 13 (06)
  • [2] The therapeutic potential of mitochondrial toxins
    Kawada, Manabu
    Amemiya, Masahide
    Yoshida, Junjiro
    Ohishi, Tomokazu
    JOURNAL OF ANTIBIOTICS, 2021, 74 (10): : 696 - 705
  • [3] The therapeutic potential of mitochondrial toxins
    Manabu Kawada
    Masahide Amemiya
    Junjiro Yoshida
    Tomokazu Ohishi
    The Journal of Antibiotics, 2021, 74 : 696 - 705
  • [4] Natural toxins and their therapeutic potential
    Kapoor, V. K.
    INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY, 2010, 48 (03) : 228 - 237
  • [5] In vivo effects of cnidarian toxins and venoms
    Suput, Dusan
    TOXICON, 2009, 54 (08) : 1190 - 1200
  • [6] Enhancing the therapeutic potential of peptide toxins
    Norton, Raymond S.
    EXPERT OPINION ON DRUG DISCOVERY, 2017, 12 (06) : 611 - 623
  • [7] SPECIAL ISSUE: Cnidarian Toxins and Venoms Preface
    Kem, W. R.
    Turk, T.
    TOXICON, 2009, 54 (08) : 1029 - 1029
  • [8] Recent advances in the therapeutic uses of chondroitinase ABC
    Muir, E.
    De Winter, F.
    Verhaagen, J.
    Fawcett, J.
    EXPERIMENTAL NEUROLOGY, 2019, 321
  • [9] The Development of Toad Toxins as Potential Therapeutic Agents
    Qi, Ji
    Zulfiker, Abu Hasanat Md
    Li, Chun
    Good, David
    Wei, Ming Q.
    TOXINS, 2018, 10 (08)
  • [10] Wasp Venom Toxins as a Potential Therapeutic Agent
    Dongol, Yashad
    Dhananjaya, Bhadrapara L.
    Shrestha, Rakesh K.
    Aryal, Gopi
    PROTEIN AND PEPTIDE LETTERS, 2016, 23 (08): : 688 - 698