The Pro-autoimmune allele of tyrosine phosphatase PTPN22 enhances anti-viral and anti-tumor immunity

被引:0
|
作者
Orozco, Robin C. [1 ]
Marquardt, Kristi [1 ]
Mowen, Kerri A. [1 ]
Pratumchai, Isaraphorn [1 ,2 ]
Teijaro, John R. [1 ]
Sherman, Linda A. [1 ]
机构
[1] Scripps Res Inst, Dept Immunol & Microbiol, San Diego, CA USA
[2] Leiden Univ, Dept Chem Immunol, Med Ctr, Leiden, Netherlands
来源
JOURNAL OF IMMUNOLOGY | 2020年 / 204卷 / 01期
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
247.3
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Viral and tumor immunity is enhanced in mice expressing the pro-autoimmune allele of tyrosine phosphatase Ptpn22
    Orozco, Robin C.
    Marquardt, Kristi
    Mowen, Kerri A.
    Pratumchai, Isaraphorn
    Teijaro, John R.
    Sherman, Linda A.
    JOURNAL OF IMMUNOLOGY, 2021, 206
  • [2] Dendritic cell intrinsic role of Ptpn22 and its pro-autoimmune allele enhance anti-viral immunity
    Orozco, Robin C.
    Shaikh, Anam
    Nasiri, Saeideh
    Barnes, Jenna
    Howard, Andrew
    Orozco, Robin
    JOURNAL OF IMMUNOLOGY, 2023, 210 (01):
  • [3] Autoimmunity-associated allele of tyrosine phosphatase gene PTPN22 enhances anti-viral immunity
    Orozco, Robin C.
    Marquardt, Kristi
    Pratumchai, Isaraphorn
    Shaikh, Anam Fatima
    Mowen, Kerri
    Domissy, Alain
    Teijaro, John R.
    Sherman, Linda A.
    PLOS PATHOGENS, 2024, 20 (03)
  • [4] Tumor immunity is enhanced in mice expressing the pro-autoimmune allele of tyrosine phosphatase Ptpn22, but not in Ptpn22 knock-out mice
    Orozco, Robin C.
    Marquardt, Kristi
    Mowen, Kerri A.
    Sherman, Linda A.
    JOURNAL OF IMMUNOLOGY, 2022, 208 (01):
  • [5] Proautoimmune Allele of Tyrosine Phosphatase, PTPN22, Enhances Tumor Immunity
    Orozco, Robin C.
    Marquardt, Kristi
    Mowen, Kerri
    Sherman, Linda A.
    JOURNAL OF IMMUNOLOGY, 2021, 207 (06): : 1662 - 1671
  • [6] Dendritic cell-intrinsic PTPN22 negatively regulates anti-tumor immunity
    Acero-Bedoya, Santiago
    Higgs, Emily F.
    Gajewski, Thomas F.
    CANCER RESEARCH, 2022, 82 (12)
  • [7] DENDRITIC CELL-INTRINSIC PTPN22 NEGATIVELY REGULATES ANTI-TUMOR IMMUNITY
    Acero-Bedoya, Santiago
    Gajewski, Thomas
    Higgs, Emily
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 10 : A1020 - A1020
  • [8] Roles of the protein tyrosine phosphatase PTPN22 in immunity and autoimmunity
    Fousteri, Georgia
    Liossis, Stamatis-Nick C.
    Battaglia, Manuela
    CLINICAL IMMUNOLOGY, 2013, 149 (03) : 556 - 565
  • [9] The pleiotropic effects of PTPN22 and its pro-autoimmune alternative allele on the antiviral immune response and T cell exhaustion
    Orozco, Robin C.
    Marquardt, Kristi
    Mowen, Kerri A.
    Pratumchai, Isaraphorn
    Teijaro, John R.
    Sherman, Linda A.
    JOURNAL OF IMMUNOLOGY, 2019, 202 (01):
  • [10] The tryptophan 620 allele of the lymphoid tyrosine phosphatase (PTPN22) gene predisposes to autoimmune Addison's disease
    Roycroft, Matthew
    Fichna, Marta
    McDonald, David
    Owen, Kate
    Zurawek, Magdalena
    Gryczynska, Maria
    Januszkiewicz-Lewandowska, Danuta
    Fichna, Piotr
    Cordell, Heather
    Donaldson, Peter
    Nowak, Jerzy
    Pearce, Simon
    CLINICAL ENDOCRINOLOGY, 2009, 70 (03) : 358 - 362