Cu(OAc)2-Catalyzed Aerobic Oxidative Dehydrogenation Coupling: Synthesis of Heptacyclic Quinolizino[3,4,5,6-kla]perimidines

被引：39
|
作者：
Feng, Bin-Bin [1 ]
Liu, Jian-Quan [1 ]
Wang, Xiang-Shan [1 ]
机构：
[1] Jiangsu Normal Univ, Sch Chem & Chem Engn, Jiangsu Key Lab Green Synth Funct Mat, Xuzhou 221116, Jiangsu, Peoples R China
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 82卷 / 03期
关键词：
BOND FORMATION; DERIVATIVES; ARYLATION; CYCLIZATION; ACTIVATION; THIOPHENES; CLEAVAGE; RHODIUM; ARENES;
D O I：
10.1021/acs.joc.6b02644
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A Cu(OAc)(2)-catalyzed domino tricyclization between naphthalene-1,8-diamine and 2-(phenylethynyl)-benzaldehyde is described, enabling aerobic oxidative dehydrogenation coupling to access heptacyclic quinolizino[3,4,5,6-kla]perimidines. In this reaction, the formation of three new rings and four new bonds was achieved in a functional-group-compatible fashion, allowing a facile method toward fused azaheterocycles containing both quinolizine and perimidine moieties.
引用
收藏
页码：1817 / 1822
页数：6
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