Efficient synthesis of 1-(4'-methylbenzoyl)-3,3-diethylthiourea under microwave irradiation using potassium fluoride on alumina

被引：28
|
作者：
Márquez, H
Plutín, A
Rodríguez, Y
Perez, E
Loupy, A [2 ]
机构：
[1] Univ La Habana, Fac Quim, Lab Sintesis Organ, La Habana, Cuba
[2] Univ Paris Sud, Lab React Select Supports, ICMO, UMR 8615, F-91405 Orsay, France
来源：
SYNTHETIC COMMUNICATIONS | 2000年 / 30卷 / 06期
关键词：
D O I：
10.1080/00397910008087124
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
1,1-diethylthiourea and 4-methylbenzoic acid were condensed to 1-(4'-methylbenzoyl)-3,3-diethylthiourea in open vessels under microwave irradiation using an unmodified domestic microwave oven. The synthesis was carried out in the presence of alumina impregnated with potassium fluoride and catalytic amounts of N,N-dimethylformamide. The yields are noticeably improved in comparison with classical methods.
引用
收藏
页码：1067 / 1073
页数：7
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