Spectral Studies on the Interaction of [Ru(bpy)2(BTIP)]2+ with DNA and Determination of Nucleic Acids at Nanogram Levels

被引：0
|
作者：
Weng, Chao [1 ]
Chen, Xiaoming
Cai, Changqun
机构：
[1] Xiangtan Univ, Coll Chem, Xiangtan 411105, Peoples R China
来源：
SPECTROSCOPY | 2009年 / 24卷 / 06期
关键词：
RESONANCE LIGHT-SCATTERING; SWITCH COMPLEX; CETYLTRIMETHYLAMMONIUM BROMIDE; SENSITIVE DETERMINATION; METAL-COMPLEXES; RUTHENIUM(II); ENHANCEMENT; PROTEINS; ASSAY; BINDING;
D O I：
暂无
中图分类号：
O433 [光谱学];
学科分类号：
0703 ; 070302 ;
摘要：
The interaction of [Ru(2, 2'-bipyridine)2(2-benzo[b] thien-2-yl-1H-imidazo[4,5-f][1,10] phen-anthroline)](2+) ([Ru(bpy)(2)(BTIP)](2+)) with nucleic acids in weak acidic medium is studied based upon the measurements of resonance light scattering (RLS) and UV-vis absorbance. Intercalation, electrostatic interaction, and long-range assembly are observed between [Ru(bpy)(2)(BTIP)](2+) and calf-thymus DNA (ctDNA). The enhanced RLS intensity is proportional to the concentration of ctDNA in an appropriate range. Three synthetic samples are analyzed satisfactorily.
引用
收藏
页码：39 / 44
页数：6
相关论文
共 50 条
  • [1] Spectral studies on the interaction of DNA and Ru(bipy)2(dppx)2+
    Ling, LS
    He, ZK
    Zeng, YE
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 1999, 55 (06) : 1297 - 1302
  • [2] Synthesis, DNA-binding and photocleavage studies of ruthenium complexes [Ru(bpy)2(mitatp)]2+ and [Ru(bpy)2(nitatp)]2+
    Yu, Hui-Juan
    Huang, Shu-Mei
    Li, Lv-Ying
    Jia, Hai-Na
    Chao, Hui
    Mao, Zong-Wan
    Liu, Jian-Zhong
    Ji, Liang-Nian
    JOURNAL OF INORGANIC BIOCHEMISTRY, 2009, 103 (06) : 881 - 890
  • [3] Synthesis, characterization and DNA binding studies of ruthenium(II) complexes: [Ru(bpy)2(dtmi)]2+ and [Ru(bpy)2(dtni)]2+
    Yun-Jun Liu
    Xin Yu Wei
    Wen-Jie Mei
    Li-Xin He
    Transition Metal Chemistry, 2007, 32 : 762 - 768
  • [4] Synthesis, characterization and DNA binding studies of ruthenium(II) complexes:: [Ru(bpy)2(dtmi)]2+ and [Ru(bpy)2(dtni)]2+
    Liu, Yun-Jun
    Wei, Xin Yu
    Mei, Wen-Jie
    He, Li-Xin
    TRANSITION METAL CHEMISTRY, 2007, 32 (06) : 762 - 768
  • [5] DNA INTERACTION AND PHOTOCLEAVAGE PROPERTIES OF RU (II) COMPLEXES [RU(bpy)2(pibi)]2+ AND [Ru(phen)2(pibi)]2+
    Liu, XueWen
    Li, ZhiXin
    Hu, Xia
    Zhang, SongBai
    Lu, JiLin
    NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2014, 33 (08): : 519 - 535
  • [6] Studies on interactions of ruthenium(II) polypyridyl complexes [Ru (bpy)2 (btip)] 2+and [Ru(dmb)2(btip)]2+ with double-stranded RNA poly (A)•poly(U) under molecular crowding conditions
    Wen, Bingxin
    Tan, Lifeng
    INORGANICA CHIMICA ACTA, 2024, 569
  • [7] DNA Condensation Induced by Ruthenium(II) Polypyridyl Complexes [Ru(bpy)2(PIPSH)]2+ and [Ru(bpy)2(PIPNH)]2+
    Sun, Bin
    Guan, Jing-Xin
    Xu, Li
    Yu, Bo-Le
    Jiang, Long
    Kou, Jun-Feng
    Wang, Li
    Ding, Xi-Dong
    Chao, Hui
    Ji, Liang-Nian
    INORGANIC CHEMISTRY, 2009, 48 (11) : 4637 - 4639
  • [8] Synthesis, characterization, DNA-binding and photocleavage studies of [Ru(bpy)2(PPIP)]2+ and [Ru(phen)2(PPIP)]2+
    Tan, LF
    Chao, H
    Li, H
    Liu, YJ
    Sun, B
    Wei, W
    Ji, LN
    JOURNAL OF INORGANIC BIOCHEMISTRY, 2005, 99 (02) : 513 - 520
  • [9] Synthesis, DNA binding, and DNA photocleavage of the ruthenium(II) complexes [Ru(bpy)(btip)]2+ and [Ru(dmb)(btip)]2+ (bpy=2,2′-bipyridine; btip=2-benzo[b]thien-2-yl-1H-imidazo[4,5-f] [1,10]phenanthroline; dmb=4,4′-dimethyl-2,2′-bipyridine)
    Tan, Li-Feng
    Wang, Fang
    Chao, Hui
    HELVETICA CHIMICA ACTA, 2007, 90 (01) : 205 - 215
  • [10] Studies on the interaction of copper complexes of [Cu(phen)2]2+ and [Cu(bpy)2]2+ with DNA by microcalorimetry
    Yi, PG
    Shang, ZC
    Yu, QS
    CHINESE JOURNAL OF INORGANIC CHEMISTRY, 2001, 17 (01) : 77 - 82
12345