Ascl1 reprograms Muller glia into functional retinal neurons

被引:0
|
作者
Pollak, Julia [1 ,2 ]
Wilken, Matthew [1 ,3 ]
Ueki, Yumi [1 ]
Cox, Kristin [1 ]
Taylor, Russell [1 ]
Reh, Thomas [1 ,2 ]
机构
[1] Univ Washington, Dept Biol Struct, Seattle, WA 98195 USA
[2] Univ Washington, Neurobiol & Behav Program, Seattle, WA 98195 USA
[3] Univ Washington, Mol & Cellular Biol Program, Seattle, WA 98195 USA
关键词
688; retina; 603 Muller cells; 687; regeneration;
D O I
暂无
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
1396
引用
收藏
页数:2
相关论文
共 50 条
  • [1] ASCL1 reprograms mouse Muller glia into neurogenic retinal progenitors
    Pollak, Julia
    Wilken, Matthew S.
    Ueki, Yumi
    Cox, Kristen E.
    Sullivan, Jane M.
    Taylor, Russell J.
    Levine, Edward M.
    Reh, Thomas A.
    DEVELOPMENT, 2013, 140 (12): : 2619 - 2631
  • [2] Transgenic expression of the proneural transcription factor Ascl1 in Muller glia stimulates retinal regeneration in young mice
    Ueki, Yumi
    Wilken, Matthew S.
    Cox, Kristen E.
    Chipman, Laura
    Jorstad, Nikolas
    Sternhagen, Kristen
    Simic, Milesa
    Ullom, Kristy
    Nakafuku, Masato
    Reh, Thomas A.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 112 (44) : 13717 - 13722
  • [3] Involvement of Lin28 and Ascl1 in Muller Glia-mediated neurogenesis
    Mir, Qulsum A.
    Zheng, Li
    Ahmad, Iqbal
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2015, 56 (07)
  • [4] miR-25 reprograms murine primary Muller glia into functional mature neurons
    Kang, S.
    Srinivas, M.
    Wohl, S.
    GLIA, 2023, 71 : E1127 - E1127
  • [5] Ascl1 Converts Dorsal Midbrain Astrocytes into Functional Neurons In Vivo
    Liu, Yueguang
    Miao, Qinglong
    Yuan, Jiacheng
    Han, Su'e
    Zhang, Panpan
    Li, Sanlan
    Rao, Zhiping
    Zhao, Wenlong
    Ye, Qian
    Geng, Junlan
    Zhang, Xiaohui
    Cheng, Leping
    JOURNAL OF NEUROSCIENCE, 2015, 35 (25): : 9336 - 9355
  • [6] ASCL1 induces neurogenesis in human Möller glia
    Wohlschlegel, Juliette
    Finkbeiner, Connor
    Hoffer, Dawn
    Kierney, Faith
    Prieve, Aric
    Murry, Alexandria D.
    Haugan, Alexandra K.
    Ortuno-Lizaran, Isabel
    Rieke, Fred
    Golden, Sam A.
    Reh, Thomas A.
    STEM CELL REPORTS, 2023, 18 (12): : 2400 - 2417
  • [7] Reprogramming Muller Glia to Regenerate Retinal Neurons
    Lahne, Manuela
    Nagashima, Mikiko
    Hyde, David R.
    Hitchcock, Peter F.
    ANNUAL REVIEW OF VISION SCIENCE, VOL 6, 2020, 2020, 6 : 171 - 193
  • [8] Involvement of HB-EGF/Ascl1/Lin28a Genes in Dedifferentiation of Adult Mammalian Muller Glia
    Stanchfield, Megan L.
    Webster, Sarah E.
    Webster, Mark K.
    Linn, Cindy L.
    FRONTIERS IN MOLECULAR BIOSCIENCES, 2020, 7
  • [9] STAT Signaling Modifies Ascl1 Chromatin Binding and Limits Neural Regeneration from Muller Glia in Adult Mouse Retina
    Jorstad, Nikolas L.
    Wilken, Matthew S.
    Todd, Levi
    Finkbeiner, Connor
    Nakamura, Paul
    Radulovich, Nicholas
    Hooper, Marcus J.
    Chitsazan, Alex
    Wilkerson, Brent A.
    Rieke, Fred
    Reh, Thomas A.
    CELL REPORTS, 2020, 30 (07): : 2195 - 2208
  • [10] Distinct requirements for Ascl1 in subpopulations of midbrain GABAergic neurons
    Peltopuro, Paula
    Kala, Kaia
    Partanen, Juha
    DEVELOPMENTAL BIOLOGY, 2010, 343 (1-2) : 63 - 70