Progression-free survival: too much risk, not enough reward?

被引：15

作者：

Alexander, Brian M. ^{[1
]}

Trippa, Lorenzo ^{[2
,3
]}

机构：

[1] Harvard Univ, Sch Med, Dept Radiat Oncol, Dana Farber Brigham & Womens Canc Ctr, Boston, MA USA

[2] Dana Farber Canc Inst, Dept Biostat & Computat Biol, Boston, MA 02215 USA

[3] Harvard Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02115 USA

来源：

NEURO-ONCOLOGY | 2014年 / 16卷 / 05期

关键词：

D O I：

10.1093/neuonc/nou041

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：615 / 616

页数：2

共 7 条

[1] Detecting an Overall Survival Benefit that Is Derived From Progression-Free Survival [J].

Broglio, Kristine R. ;

Berry, Donald A. .

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2009, 101 (23) :1642-1649

[2]

Chinot OL, 2014, NEW ENGL J MED, V370, P709, DOI 10.1056/NEJMoa1308345

[3] A Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma [J].

Gilbert, Mark R. ;

Dignam, James J. ;

Armstrong, Terri S. ;

Wefel, Jeffrey S. ;

Blumenthal, Deborah T. ;

Vogelbaum, Michael A. ;

Colman, Howard ;

Chakravarti, Arnab ;

Pugh, Stephanie ;

Won, Minhee ;

Jeraj, Robert ;

Brown, Paul D. ;

Jaeckle, Kurt A. ;

Schiff, David ;

Stieber, Volker W. ;

Brachman, David G. ;

Werner-Wasik, Maria ;

Tremont-Lukats, Ivo W. ;

Sulman, Erik P. ;

Aldape, Kenneth D. ;

Curran, Walter J., Jr. ;

Mehta, Minesh P. .

NEW ENGLAND JOURNAL OF MEDICINE, 2014, 370 (08) :699-708

[4] Progression-free survival as a surrogate endpoint for overall survival in glioblastoma: a literature-based meta-analysis from 91 trials [J].

Han, Kelong ;

Ren, Melanie ;

Wick, Wolfgang ;

Abrey, Lauren ;

Das, Asha ;

Jin, Jin ;

Reardon, David A. .

NEURO-ONCOLOGY, 2014, 16 (05) :696-706

[5] SURROGATE ENDPOINTS IN CLINICAL-TRIALS - DEFINITION AND OPERATIONAL CRITERIA [J].

PRENTICE, RL .

STATISTICS IN MEDICINE, 1989, 8 (04) :431-440

[6] Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial [J].

Stupp, Roger ;

Hegi, Monika E. ;

Mason, Warren P. ;

van den Bent, Martin J. ;

Taphoorn, Martin J. B. ;

Janzer, Robert C. ;

Ludwin, Samuel K. ;

Allgeier, Anouk ;

Fisher, Barbara ;

Belanger, Karl ;

Hau, Peter ;

Brandes, Alba A. ;

Gijtenbeek, Johanna ;

Marosi, Christine ;

Vecht, Charles J. ;

Mokhtari, Karima ;

Wesseling, Pieter ;

Villa, Salvador ;

Eisenhauer, Elizabeth ;

Gorlia, Thierry ;

Weller, Michael ;

Lacombe, Denis ;

Cairncross, J. Gregory ;

Mirimanoff, Rene-Olivier .

LANCET ONCOLOGY, 2009, 10 (05) :459-466

[7]

Terasaki M, 2013, J VACCINES VACCIN, V4, P2

← 1 →