Chiromers: conformation-driven mirror-image supramolecular chirality isomerism identified in a new class of helical rosette nanotubes

被引：20

作者：

Hemraz, Usha D. ^{[1
,2
]}

El-Bakkari, Mounir ^{[1
,2
]}

Yamazaki, Takeshi ^{[1
,2
]}

Cho, Jae-Young ^{[2
]}

Beingessner, Rachel L. ^{[2
]}

Fenniri, Hicham ^{[1
,2
,3
,4
]}

机构：

[1] Univ Alberta, Dept Chem, Edmonton, AB, Canada

[2] Natl Inst Nanotechnol, Edmonton, AB T6G 2M9, Canada

[3] Northeastern Univ, Dept Chem & Biomed Engn, Boston, MA 02115 USA

[4] Qatar Biomed Res Inst, Biomed Engn Res Ctr, Doha, Qatar

来源：

NANOSCALE | 2014年 / 6卷 / 16期

关键词：

MOLECULAR-STRUCTURE; SHAPED MOLECULES; SERGEANTS;

D O I：

10.1039/c4nr00340c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Rosette nanotubes are biologically inspired nanostructures, formed through the hierarchical organization of a hybrid DNA base analogue (GAC), which features hydrogen-bonding arrays of guanine and cytosine. Several twin-GAC motifs functionalized with chiral moieties, which undergo a self-assembly process under methanolic and aqueous conditions to produce helical rosette nanotubes (RNTs), were synthesized and characterized. The built-in molecular chirality in the twin-GAC building blocks led to the supramolecular chirality exhibited by the RNTs, as evidenced by the CD activity. Depending on the motifs and environmental conditions, mirror-image supramolecular chirality due to absolute molecular chirality, solvent-induced and structure-dependent supramolecular chirality inversion, and pH-controlled chiroptical switching were observed.

引用

页码：9421 / 9427

页数：7