The chemical constituents and biological activity of some sponges in Northern Vietnam: A review

被引：7

作者：

Phan Van Kiem ^{[1
]}

Chau Van Minh ^{[1
]}

Nguyen Xuan Nhiem ^{[1
]}

Bui Huu Tai ^{[1
]}

Pham Hai Yen ^{[1
]}

Dan Thi Thuy Hang ^{[1
]}

Duong Thi Dung ^{[1
]}

Nguyen Thi Cuc ^{[1
]}

Do Thi Trang ^{[1
]}

Duong Thi Hai Yen ^{[1
]}

Vu Van Doan ^{[1
]}

Nguyen Huy Hoang ^{[1
]}

Phan Thi Thanh Huong ^{[1
]}

Nguyen Hoai Nam ^{[1
]}

Nguyen Xuan Cuong ^{[1
]}

机构：

[1] Vietnam Acad Sci & Technol, Inst Marine Biochem, 18 Hoang Quoc Viet, Hanoi 100000, Vietnam

来源：

VIETNAM JOURNAL OF CHEMISTRY | 2019年 / 57卷 / 03期

关键词：

Sponge chemical constituent; Porifera; Vietnam marine natural product; SMENOSPONGIA-CEREBRIFORMIS; SESQUITERPENE;

D O I：

10.1002/vjch.201900041

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Chemical composition and biological activity of sponges have been studied by the authors since 2006. So far, the authors have studied about 30 species of sponges, mainly collected cross in the sea of Northern Vietnam. Over 250 compounds have been isolated and elucidated their chemical structures. Among them, there are more than 50 compounds with new chemical structures. In addition to NMR and HRMS spectra, many compounds with an unequal chemical structure are also determined by Circular Dichroism spectrometry. Some isolated compounds exhibited outstanding potential for cancer cytotoxicity and anti-inflammatory effects.

引用

页码：261 / 271

页数：11

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