Single-cell non-genetic heterogeneity confers drug resistance in melanoma

被引:0
|
作者
Shaffer, Sydney M. [1 ]
Biaesch, Andrew G. [1 ]
Torborg, Stefan [1 ]
Krepler, Clemens [2 ]
Herlyn, Meenhard [2 ]
Raj, Arjun [1 ]
机构
[1] Univ Penn, Philadelphia, PA 19104 USA
[2] Wistar Inst Anat & Biol, 3601 Spruce St, Philadelphia, PA 19104 USA
关键词
D O I
10.1158/1538-7445.FBCR15-B32
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
B32
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Non-genetic heterogeneity caused by differential single-cell adhesion
    Wang, Chun-Chao
    Janes, Kevin A.
    CELL CYCLE, 2014, 13 (14) : 2149 - 2150
  • [2] A live-cell miRNA reporter library for identifying non-genetic drug resistance networks at single-cell resolution
    Leya, Gregory
    Albeck, John
    Brugge, Joan
    CANCER RESEARCH, 2012, 72
  • [3] Profiling the Non-genetic Origins of Cancer Drug Resistance with a Single-Cell Functional Genomics Approach Using Predictive Cell Dynamics
    Meyer, Mickael
    Paquet, Agnes
    Arguel, Marie-Jeanne
    Peyre, Ludovic
    Gomes-Pereira, Luis C.
    Lebrigand, Kevin
    Mograbi, Baharia
    Brest, Patrick
    Waldmann, Rainer
    Barbry, Pascal
    Hofman, Paul
    Roux, Jeremie
    CELL SYSTEMS, 2020, 11 (04) : 367 - +
  • [4] Single-cell heterogeneity with transcriptional memory confers resistance to cancer therapy
    Shaffer, Sydney
    Emert, Benjamin
    Raj, Arjun
    CANCER RESEARCH, 2018, 78 (13)
  • [5] Tumor Heterogeneity, Single-Cell Sequencing, and Drug Resistance
    Schmidt, Felix
    Efferth, Thomas
    PHARMACEUTICALS, 2016, 9 (02)
  • [6] Non-genetic determinants of malignant clonal fitness at single-cell resolution
    Katie A. Fennell
    Dane Vassiliadis
    Enid Y. N. Lam
    Luciano G. Martelotto
    Jesse J. Balic
    Sebastian Hollizeck
    Tom S. Weber
    Timothy Semple
    Qing Wang
    Denise C. Miles
    Laura MacPherson
    Yih-Chih Chan
    Andrew A. Guirguis
    Lev M. Kats
    Emily S. Wong
    Sarah-Jane Dawson
    Shalin H. Naik
    Mark A. Dawson
    Nature, 2022, 601 : 125 - 131
  • [7] Non-genetic determinants of malignant clonal fitness at single-cell resolution
    Fennell, Katie A.
    Vassiliadis, Dane
    Lam, Enid Y. N.
    Martelotto, Luciano G.
    Balic, Jesse J.
    Hollizeck, Sebastian
    Weber, Tom S.
    Semple, Timothy
    Wang, Qing
    Miles, Denise C.
    MacPherson, Laura
    Chan, Yih-Chih
    Guirguis, Andrew A.
    Kats, Lev M.
    Wong, Emily S.
    Dawson, Sarah-Jane
    Naik, Shalin H.
    Dawson, Mark A.
    NATURE, 2022, 601 (7891) : 125 - +
  • [8] Non-genetic heterogeneity, criticality and cell differentiation
    Pal, Mainak
    Ghosh, Sayantari
    Bose, Indrani
    PHYSICAL BIOLOGY, 2015, 12 (01)
  • [9] The Genetic/Non-genetic Duality of Drug 'Resistance' in Cancer
    Salgia, Ravi
    Kulkarni, Prakash
    TRENDS IN CANCER, 2018, 4 (02): : 110 - 118
  • [10] Genetic and non-genetic drug resistance: Darwin or Lamarck?
    Russo, Mariangela
    MOLECULAR ONCOLOGY, 2024, 18 (02) : 241 - 244