Population statistics of protein structures: Lessons from structural classifications

被引：130
作者：
Brenner, SE
Chothia, C
Hubbard, TJP
机构：
[1] MRC,MOL BIOL LAB,CAMBRIDGE CB2 2QH,ENGLAND
[2] SANGER CTR,HINXTON CB10 1SA,CAMBS,ENGLAND
[3] NATL INST BIOSCI & HUMAN TECHNOL,STRUCT BIOL CTR,TSUKUBA,IBARAKI 305,JAPAN
来源：
CURRENT OPINION IN STRUCTURAL BIOLOGY | 1997年 / 7卷 / 03期
基金：
英国惠康基金;
关键词：
D O I：
10.1016/S0959-440X(97)80054-1
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Structural classifications aid the interpretation of proteins by describing degrees of structural and evolutionary relatedness. They have also recently revealed strikingly skewed distributions at all levels; for example, a small number of folds are far more common than others, and just a few superfamilies are known to have diverged widely. The classifications also provide an indication of the total number of superfamilies in nature. (C) Current Biology Ltd.
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收藏
页码：369 / 376
页数：8
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