Assessing the Potential for Unintended Microbial Consequences of Routine Chlorhexidine Bathing for Prevention of Healthcare-associated Infections

被引：17
|
作者：
Babiker, Ahmed [1 ,2 ]
Lutgring, Joseph D. [3 ]
Fridkin, Scott [1 ]
Hayden, Mary K. [4 ,5 ]
机构：
[1] Emory Univ, Div Infect Dis, Sch Med, Atlanta, GA 30322 USA
[2] Emory Univ, Dept Pathol & Lab Med, Sch Med, Atlanta, GA 30322 USA
[3] Ctr Dis Control & Prevent, Div Healthcare Qual Promot, Atlanta, GA USA
[4] Rush Univ, Dept Internal Med Infect Dis, Med Ctr, Chicago, IL USA
[5] Rush Univ, Dept Pathol, Med Ctr, Chicago, IL USA
来源：
CLINICAL INFECTIOUS DISEASES | 2021年 / 72卷 / 05期
关键词：
chlorhexidine gluconate; healthcare-associated infections; decolonization; antibiotic resistance; antiseptic; RESISTANT STAPHYLOCOCCUS-AUREUS; BLOOD-STREAM INFECTIONS; METHICILLIN-RESISTANT; ANTISEPTIC-RESISTANCE; KLEBSIELLA-PNEUMONIAE; REDUCED SUSCEPTIBILITY; HAND HYGIENE; GENES QACA; ANTIMICROBIAL RESISTANCE; ANTIBIOTIC-RESISTANCE;
D O I：
10.1093/cid/ciaa1103
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Chlorhexidine gluconate (CHG) is an antiseptic that is widely used in healthcare due to its excellent safety profile and wide spectrum of activity. Daily bathing with CHG has proven to be effective in the prevention of healthcare-associated infections and multidrug-resistant pathogen decolonization. Despite the proven benefits of CHG use, there remain concerns and unanswered questions about the potential for unintended microbial consequences of routine CHG bathing. This review aims to explore some of these questions.
引用
收藏
页码：891 / 898
页数：8
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