Mammary stem cells, where art thou?

被引：3
|
作者：
Lu, Pengfei [1 ]
Zhou, Tao [1 ]
Xu, Chongshen [1 ]
Lu, Yunzhe [1 ]
机构：
[1] ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201210, Peoples R China
来源：
WILEY INTERDISCIPLINARY REVIEWS-DEVELOPMENTAL BIOLOGY | 2019年 / 8卷 / 06期
基金：
中国国家自然科学基金;
关键词：
induced pluripotent stem cells; iPSCs; lineage tracing; mammary gland; single cell biology; GLAND DEVELOPMENT; LINEAGE COMMITMENT; PROGENITOR CELLS; SKIN APPENDAGE; DIFFERENTIATION; MORPHOGENESIS; ALVEOLAR; IDENTIFICATION; SPECIFICATION; REGENERATION;
D O I：
10.1002/wdev.357
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Tremendous progress has been made in the field of stem cell biology. This is in part due to the emergence of various vertebrate organs, including the mammary gland, as an amenable model system for adult stem cell studies and remarkable technical advances in single cell technology and modern genetic lineage tracing. In the current review, we summarize the recent progress in mammary gland stem cell biology at both the adult and embryonic stages. We discuss current challenges and controversies, and potentially new and exciting directions for future research. This article is categorized under: Adult Stem Cells, Tissue Renewal, and Regeneration > Tissue Stem Cells and Niches Adult Stem Cells, Tissue Renewal, and Regeneration > Stem Cell Differentiation and Reversion Adult Stem Cells, Tissue Renewal, and Regeneration > Regeneration
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页数：14
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