RETRACTED: Dual-Growth-Factor-Releasing PCL Scaffolds for Chondrogenesis of Adipose-Tissue-Derived Mesenchymal Stem Cells (Retracted Article)

被引：11
|
作者：
Lim, Sung Mook [1 ]
Jang, Sung Hwan [1 ]
Oh, Se Heang [1 ]
Yuk, Soon Hong [1 ]
Im, Gun Il [2 ]
Lee, Jin Ho [1 ]
机构：
[1] Hannam Univ, Dept Adv Mat, Taejon 305811, South Korea
[2] Dongguk Univ, Int Hosp, Dept Orthoped, Goyang 411373, South Korea
来源：
ADVANCED ENGINEERING MATERIALS | 2010年 / 12卷 / 1-2期
关键词：
CALCIUM-PHOSPHATE; HYDROXYAPATITE; ELECTRODEPOSITION; COATINGS; TITANIUM; IMPLANT; MICROSTRUCTURE; DEPOSITION; MORPHOLOGY; ALLOYS;
D O I：
10.1002/adem.200980153
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Polycaprolactone/Pluronic F127 porous scaffolds are prepared using a modified melt-molding particulate-leaching method. The scaffolds are highly porous (about 90% porosity) and have open-cellular pore structures. Growth factors (TGF-beta(2), BMP-7 or dual TGF-beta(2)/BMP-7) can be easily immobilized on the pore surfaces of the PCL/F127 scaffolds via binding with heparin. The growth-factor-immobilized scaffolds can induce the chondrogenesis of ATMSCs seeded onto them. Using TGF-beta(2) and BMP-7 growth factors together leads to a better chondrogenic differentiation behavior than using single-growth-factor immobilized scaffolds.
引用
收藏
页码：B62 / B73
页数：12
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