The PI3K-AKT pathway - a therapeutic target in melanoma brain metastases?

被引:0
|
作者
Niessner, H. [1 ]
Schmitz, J. [2 ]
Schmid, A. [2 ]
Sinnberg, T. [1 ]
Tabatabai, G. [3 ]
Weide, B. [1 ]
Garbe, C. [1 ]
Quintanilla-Fend, L. [4 ]
Mai, M. [5 ]
Beissert, S. [5 ]
Kulms, D. [5 ]
Schackert, G. [6 ]
Muders, M. [7 ]
Meinhardt, M. [7 ]
Baretton, G. [7 ]
Pichler, B. [2 ]
Westphal, D. [5 ]
Meier, F. [1 ,5 ]
机构
[1] Univ Tubingen, Dept Dermatol, D-72076 Tubingen, Germany
[2] Univ Tubingen, Dept Preclin Imaging & Radiopharm, D-72076 Tubingen, Germany
[3] Univ Tubingen, Dept Neurol, D-72076 Tubingen, Germany
[4] Univ Tubingen, Dept Pathol, D-72076 Tubingen, Germany
[5] Tech Univ Dresden, Dept Dermatol, Carl Gustav Carus Med Ctr, Dresden, Germany
[6] Tech Univ Dresden, Dept Neurosurg, Carl Gustav Carus Med Ctr, Dresden, Germany
[7] Tech Univ Dresden, Dept Pathol, Carl Gustav Carus Med Ctr, Dresden, Germany
关键词
D O I
暂无
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
P209
引用
收藏
页码:E35 / E35
页数:1
相关论文
共 50 条
  • [1] The Role of the PI3K-AKT Pathway in Melanoma
    Davies, Michael A.
    CANCER JOURNAL, 2012, 18 (02): : 142 - 147
  • [2] The PI3K-AKT pathway: A plausible therapeutic target in Parkinson's disease
    Goyal, Ahsas
    Agrawal, Anant
    Verma, Aanchal
    Dubey, Nandini
    EXPERIMENTAL AND MOLECULAR PATHOLOGY, 2022, 129
  • [3] The multi-faceted roles of the PI3K-AKT pathway in melanoma
    Michael A Davies
    Journal of Translational Medicine, 13 (Suppl 1)
  • [4] The PI3K/Akt/mTOR pathway as a preventive target in melanoma brain metastasis
    Tehranian, Cedric
    Fankhauser, Laura
    Harter, Patrick N.
    Ratcliffe, Colin D. H.
    Zeiner, Pia S.
    Messmer, Julia M.
    Hoffmann, Dirk C.
    Frey, Katharina
    Westphal, Dana
    Ronellenfitsch, Michael W.
    Sahai, Erik
    Wick, Wolfgang
    Karreman, Matthia A.
    Winkler, Frank
    NEURO-ONCOLOGY, 2022, 24 (02) : 213 - 225
  • [5] FUNCTIONAL STUDIES AND POTENTIAL THERAPEUTIC APPROACHES IN DISORDERS OF THE PI3K-AKT PATHWAY
    Boccuto, Luigi
    Cascio, Lauren
    Dyment, David
    Jones, Kelly
    Norris, Joy
    Chen, Chin-Fu
    Skinner, Cindy
    Basel-Vanagaite, Lina
    Stevenson, Roger
    Innes, Micheil
    Schwartz, Charles
    AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 2015, 167 (08) : 1725 - 1726
  • [6] Inhibition of the PI3K-AKT signalling pathway to overcome therapy resistance in melanoma-derived brain metastasis
    Niessner, H.
    Adam, A.
    Bornemann, A.
    Honegger, J. B.
    Hoek, K.
    Quintanilla-Fend, L.
    Meier, F.
    EXPERIMENTAL DERMATOLOGY, 2011, 20 (02) : 194 - 194
  • [7] Methylation among members of the PI3K/AKT/mTOR pathway in melanoma brain and extracerebral metastases
    Meier, Friedegund Elke
    Westphal, Dana
    Meinhardt, Matthias
    Gruetzmann, Konrad
    Schrimpf, Daniel
    Aust, Daniela Ellen
    Schroeck, Evelin
    Baretton, Gustavo Bruno
    Beissert, Stefan
    Schackert, Gabriele
    von Deimling, Andreas
    Koelsche, Christian
    Klink, Barbara
    Muders, Michael
    Seifert, Michael
    JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (15)
  • [8] Molecular Profiling of Patient-Matched Brain and Extracranial Melanoma Metastases Implicates the PI3K Pathway as a Therapeutic Target
    Chen, Guo
    Chakravarti, Nitin
    Aardalen, Kimberly
    Lazar, Alexander J.
    Tetzlaff, Michael T.
    Wubbenhorst, Bradley
    Kim, Sang-Bae
    Kopetz, Scott
    Ledoux, Alicia A.
    Gopal, Y. N. Vashisht
    Pereira, Cristiano Goncalves
    Deng, Wanleng
    Lee, Ju-Seog
    Nathanson, Katherine L.
    Aldape, Kenneth D.
    Prieto, Victor G.
    Stuart, Darrin
    Davies, Michael A.
    CLINICAL CANCER RESEARCH, 2014, 20 (21) : 5537 - 5546
  • [9] Targeting the PI3K-Akt pathway in kidney cancer
    Park, Jin-Young
    Lin, Pei-Yin
    Weiss, Robert H.
    EXPERT REVIEW OF ANTICANCER THERAPY, 2007, 7 (06) : 863 - 870
  • [10] CTCFL regulates the PI3K-Akt pathway and it is a target for personalized ovarian cancer therapy
    Marisol Salgado-Albarrán
    Julian Späth
    Rodrigo González-Barrios
    Jan Baumbach
    Ernesto Soto-Reyes
    npj Systems Biology and Applications, 8