Establishment and Characterization of Bortezomib-Resistant Myeloma Cell Lines: A Possible Role of Mutated Proteasome β5 Subunit in Preventing the Accumulation of Unfolded Protein, Which Is Otherwise Followed by Catastrophic Endoplasmic Reticulum (ER) Stress

被引:0
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作者
Ri, Masaki [1 ]
Iida, Shinsuke [1 ]
Nakashima, Takayuki [2 ]
Miyazaki, Hideyuki [2 ]
Mori, Fumiko [1 ]
Ito, Asahi [1 ]
Inagaki, Atsushi [1 ]
Kusumoto, Shigeru [1 ]
Ishida, Takashi [1 ]
Komatsu, Hirokazu [1 ]
Shiotsu, Yukimasa [2 ]
Ueda, Ryuzo [1 ]
机构
[1] Nagoya City Univ, Grad Sch Med Sci, Dept Med Oncol & Immunol, Nagoya, Aichi, Japan
[2] Kyowa Hakko Kirin Co Ltd, Div Res, Shizuoka, Japan
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R5 [内科学];
学科分类号
1002 ; 100201 ;
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页码:1451 / 1451
页数:1
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    M Ri
    S Iida
    T Nakashima
    H Miyazaki
    F Mori
    A Ito
    A Inagaki
    S Kusumoto
    T Ishida
    H Komatsu
    Y Shiotsu
    R Ueda
    Leukemia, 2010, 24 : 1506 - 1512
  • [2] Bortezomib-resistant myeloma cell lines: a role for mutated PSMB5 in preventing the accumulation of unfolded proteins and fatal ER stress
    Ri, M.
    Iida, S.
    Nakashima, T.
    Miyazaki, H.
    Mori, F.
    Ito, A.
    Inagaki, A.
    Kusumoto, S.
    Ishida, T.
    Komatsu, H.
    Shiotsu, Y.
    Ueda, R.
    LEUKEMIA, 2010, 24 (08) : 1506 - 1512