Influence of alcohols on the critical micelle concentration of heptacainiurn chloride.: Study of local anesthetics, part 171

被引:0
|
作者
Andriamainty, F. [1 ]
Cizmarik, J. [1 ]
Zudorova, Z. [1 ]
Malik, I. [1 ]
Sedlarova, E. [1 ]
机构
[1] Fac Pharm UK, Bratislava 83232, Slovakia
来源
PHARMAZIE | 2007年 / 62卷 / 01期
关键词
D O I
10.1691/ph.2007.1.6146
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The critical micelle concentrations (CIVIC), of heptacainium chloride in various 0.5 M alcohols (methanol, ethanol and n-propanol) were determined using spectrophotometric measurements. CMC values were determined through the change in the slope when the absorbance versus surfactant concentration was plotted at 234 nm. The CMC values show that micelle formation occurred more easily in methanol than in other higher alcohols.
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页码:77 / 78
页数:2
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