Dynamin family of mechanoenzymes

被引:149
作者
Danino, D [1 ]
Hinshaw, JE [1 ]
机构
[1] NIH, Lab Cell Biochem & Biol, Bethesda, MD 20892 USA
关键词
D O I
10.1016/S0955-0674(00)00236-2
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The dynamin family of proteins is continually growing, and in recent years members have been localized to areas of mitochondrial fission, plant phragmoplasts and chloroplasts, and viral ribonucleoprotein complexes. All the dynamin-like proteins examined to-date appear to assemble into oligomers, such as rings or spirals; however, it remains to be determined if a global mechanism of action exists. Even the role of dynamin in vesicle formation remains controversial as to whether it behaves as a molecular switch or as a mechanochemical enzyme.
引用
收藏
页码:454 / 460
页数:7
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