Glucose lowering efficacy of Ficus racemosa bark extract in normal and alloxan diabetic rats

被引：37
|
作者：
Rao, RB [1 ]
Murugesan, T [1 ]
Sinha, S [1 ]
Saha, BP [1 ]
Pal, M [1 ]
Mandal, SC [1 ]
机构：
[1] Jadavpur Univ, Dept Pharmaceut Technol, Kolkata 700032, W Bengal, India
来源：
PHYTOTHERAPY RESEARCH | 2002年 / 16卷 / 06期
关键词：
Ficus racemosa; Ficus glomerata; bark extract; hypoglycaemic activity; MEBFR;
D O I：
10.1002/ptr.988
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The glucose-lowering efficacy of a methanol extract of the stem bark of Ficus raccmosa Linn. (MEBFR) (Family Moraceae) was evaluated both in normal and alloxan-induced diabetic rats. The MEBFR at the doses examined (200 and 400 mg/kg p.o.) exhibited significant hypoglycaemic activity in both experimental animal models when compared with the control group. The activity was also comparable to that of the effect produced by a standard antidiabetic agent, glibenclamide 10 mg/kg. The present investigation established pharmacological evidence to support the folklore claim that it is an antidiabetic agent. Copyright (C) 2002 John Wiley Sons, Ltd.
引用
收藏
页码：590 / 592
页数：3
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