This study presents an updated list of leaf beetles from Mexico (Coleoptera: Megalopodidae, Orsodacnidae, and Chrysomelidae). The first record of Physonota gigantea Boheman from Mexico is reported, and new state records for 16 species are also reported from the specimens examined in Mexican collections (CCFES-Z, CNIN, CNRF, IEXA). Synonyms and the state geographic distribution for each species is provided. In total, 2,556 valid species and 127 subspecies are hitherto known, Megalopodidae comprises 31 species belonging to 3 genera, Orsodacnidae comprises 17 species belonging to 2 genera, and Chrysomelidae includes 2,508 species in 327 genera. Acanthoscelides with 122 species, Lema with 96 species, Pachybrachis with 84 species, Cryptocephalus with 77 species, and Chlamisus with 57 species, were the most diverse genera. The Mexican states with the highest number of leaf beetles were Veracruz with 945 species, Oaxaca with 799, Guerrero with 654, and Morelos with 535 species.