Depletion of the mammalian ER translocase subunit Sec61α and two resulting phenotypes: Impacts on protein translocation into the ER and Ca2+ leakage from the ER

被引：0
|
作者：
Lang, Sven [1 ]
Zimmermann, R. Z. [1 ]
机构：
[1] Univ Saarland, Fac Med, Saarland, Germany
来源：
BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE | 2011年 / 89卷 / 02期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：273 / 273
页数：1
相关论文
共 22 条
  • [1] BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER
    Schaeuble, Nico
    Lang, Sven
    Jung, Martin
    Cappel, Sabine
    Schorr, Stefan
    Ulucan, Oezlem
    Linxweiler, Johannes
    Dudek, Johanna
    Blum, Robert
    Helms, Volkhard
    Paton, Adrienne W.
    Paton, James C.
    Cavalie, Adolfo
    Zimmermann, Richard
    EMBO JOURNAL, 2012, 31 (15): : 3282 - 3296
  • [2] Sec61 complexes form ubiquitous ER Ca2+ leak channels
    Lang, Sven
    Erdmann, Frank
    Jung, Martin
    Wagner, Richard
    Cavalie, Adolfo
    Zimmermann, Richard
    CHANNELS, 2011, 5 (03) : 228 - 235
  • [3] Surfing the Sec61 channel:: bidirectional protein translocation across the ER membrane
    Römisch, K
    JOURNAL OF CELL SCIENCE, 1999, 112 (23) : 4185 - 4191
  • [4] BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER (vol 31, pg 3282, 2012)
    Schaeuble, Nico
    Lang, Sven
    Jung, Martin
    Cappel, Sabine
    Schorr, Stefan
    Ulucan, Oezlem
    Linxweiler, Johannes
    Dudek, Johanna
    Blum, Robert
    Helms, Volkhard
    Paton, Adrienne W.
    Paton, James C.
    Cavalie, Adolfo
    Zimmermann, Richard
    EMBO JOURNAL, 2012, 31 (18): : 3784 - 3784
  • [5] Sec61 channel subunit Sbh1/Sec61β promotes ER translocation of proteins with suboptimal targeting sequences and is fine-tuned by phosphorylation
    Barbieri, Guido
    Simon, Julien
    Lupusella, Cristina R.
    Pereira, Fabio
    Elia, Francesco
    Meyer, Hadar
    Schuldiner, Maya
    Hanes, Steven D.
    Nguyen, Duy
    Helms, Volkhard
    Roemisch, Karin
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2023, 299 (03)
  • [6] Nogo-C regulates post myocardial infarction fibrosis through the interaction with ER Ca2+ leakage channel Sec61α in mouse hearts
    Lin Weng
    Shi Jia
    Chunling Xu
    Jingjing Ye
    Yangpo Cao
    Yingying Liu
    Ming Zheng
    Cell Death & Disease, 9
  • [7] Nogo-C regulates post myocardial infarction fibrosis through the interaction with ER Ca2+ leakage channel Sec61α in mouse hearts
    Weng, Lin
    Jia, Shi
    Xu, Chunling
    Ye, Jingjing
    Cao, Yangpo
    Liu, Yingying
    Zheng, Ming
    CELL DEATH & DISEASE, 2018, 9
  • [8] Interaction of calmodulin with Sec61α limits Ca2+ leakage from the endoplasmic reticulum
    Erdmann, Frank
    Schaeuble, Nico
    Lang, Sven
    Jung, Martin
    Honigmann, Alf
    Ahmad, Mazen
    Dudek, Johanna
    Benedix, Julia
    Harsman, Anke
    Kopp, Annika
    Helms, Volkhard
    Cavalie, Adolfo
    Wagner, Richard
    Zimmermann, Richard
    EMBO JOURNAL, 2011, 30 (01): : 17 - 31
  • [9] Sec61 complex/translocon: The role of an atypical ER Ca2+-leak channel in health and disease
    Parys, Jan B.
    Van Coppenolle, Fabien
    FRONTIERS IN PHYSIOLOGY, 2022, 13
  • [10] The novel endoplasmic reticulum (ER)-targeted protein HAP induces cell apoptosis by the depletion of the ER Ca2+ stores
    Qu, XL
    Qi, YP
    Lan, P
    Li, QL
    FEBS LETTERS, 2002, 529 (2-3) : 325 - 331
123