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Early Juvenile Idiopathic Arthritis
被引:11
|作者:
Marzan, Katherine Anne B.
[1
]
Shaham, Bracha
[1
]
机构:
[1] USC, Childrens Hosp Los Angeles, Keck Sch Med, Div Rheumatol, Los Angeles, CA 90027 USA
关键词:
Juvenile idiopathic arthritis;
Early;
Pediatric;
Biologic therapy;
Aggressive treatment;
ALPHA MONOCLONAL-ANTIBODY;
PLACEBO-CONTROLLED TRIAL;
LONG-TERM SAFETY;
RHEUMATOID-ARTHRITIS;
OPEN-LABEL;
DOUBLE-BLIND;
ANKYLOSING-SPONDYLITIS;
ETANERCEPT TREATMENT;
EARLY PREDICTORS;
TRIAMCINOLONE ACETONIDE;
D O I:
10.1016/j.rdc.2012.04.006
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Early juvenile idiopathic arthritis (JIA) is important to recognize as timely diagnosis and treatment improves prognosis. It is a misconception that complications of JIA arise only from long-standing disease and that children will outgrow it. Early aggressive treatment is the paradigm as early disease activity has long-term consequences. There are predictors of persistent disease and joint erosions that may identify patients at higher risk. Control of disease activity within the first 6 months of onset confers improved clinical course and outcomes. The treatment perspective is thus one of early aggressive treatment for induction of disease control and ultimately remission.
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页码:355 / +
页数:20
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