Radioguided surgical strategy in mucosal melanoma of the nasal cavity

被引:16
|
作者
Baptista, Peter [2 ]
Velloso, Maria Jose Garcia [3 ]
Salvinelli, Fabrizio [1 ]
Casale, Manuele [1 ]
机构
[1] Campus Biomed Univ, Sch Med, Area Otolaryngol, I-00155 Rome, Italy
[2] Univ Navarra, Fac Med, Clin Univ, Dept Otolaryngol, Navarra, Spain
[3] Univ Navarra, Fac Med, Clin Univ, Dept Nucl Med, Navarra, Spain
关键词
mucosal melanoma; nasal cavity; radioguided surgery; gamma probe; sentinel lymph node;
D O I
10.1097/RLU.0b013e31815c5092
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Sinonasal mucosal melanoma (MM), although very rare (< 1% of the all MM), is second only to squamous cell carcinoma among cancers of the nasal region and still represents a challenging problem in head and neck cancer. A 60-year-old woman had nasal MM stage 1, which was treated with concomitant probe-guided tumor excision and an elective neck dissection after sentinel lymph node biopsy. The radioactivity status of the tumor and lymph nodes were compared with the histopathologic specimen. Surgical margins, sentinel lymph node, and lymphadenectomy were free of tumor. The patient was seen in frequent and regular follow-up and was free of disease without any other treatment (radiotherapy, immunotherapy, or chemotherapy). Radioguided surgery is an easy and reproducible surgical technique that could increase the likelihood of adequate excision and minimize the development of nodal disease by performing a "guided" neck dissection after the sentinel lymph node biopsy. A multidisciplinary approach and further studies with a longer follow-up are needed to substantiate the accuracy and safety of this strategy in the treatment of an aggressive neoplasm like MM of the head and neck, which still has a very poor prognosis.
引用
收藏
页码:14 / 18
页数:5
相关论文
共 50 条
  • [1] Primary mucosal melanoma of the nasal cavity
    Baek, CH
    Kim, KS
    Kang, MK
    OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 1996, 115 (06) : 582 - 583
  • [2] Amelanotic mucosal melanoma of the nasal cavity
    Jaiprakash, Padmapriya
    Mathew, Mary
    Singh, Varun Kumar
    Nayak, Dipak Ranjan
    JOURNAL OF THE ANATOMICAL SOCIETY OF INDIA, 2023, 72 (01) : 76 - 78
  • [3] MUCOSAL MELANOMA OF THE NASAL CAVITY AND PARANASAL SINUSES
    KINGDOM, TT
    KAPLAN, MJ
    HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 1995, 17 (03): : 184 - 189
  • [4] Mucosal melanoma of nasal cavity and paranasal sinus
    Dwivedi, Raghav
    Dwivedi, Ravi
    Kazi, Rehan
    Kumar, Sumit
    Agarwal, Satya P.
    JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, 2008, 4 (04) : 200 - 202
  • [5] Mucosal melanoma of the nasal cavity and paranasal sinuses
    Gilain, L.
    Houette, A.
    Montalban, A.
    Mom, T.
    Saroul, N.
    EUROPEAN ANNALS OF OTORHINOLARYNGOLOGY-HEAD AND NECK DISEASES, 2014, 131 (06) : 365 - 369
  • [6] Primary mucosal melanoma of the nasal cavity and paranasal sinuses
    Rinaldo, A
    Shaha, AR
    Patel, SG
    Ferlito, A
    ACTA OTO-LARYNGOLOGICA, 2001, 121 (08) : 979 - 982
  • [7] Thin on the ground: Primary mucosal melanoma of the nasal cavity
    Samar, Mirza Rameez
    Merchant, Sabrina
    Zehra, Nida E.
    Idrees, Romana
    Khan, Saqib Raza
    INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 2023, 111
  • [8] Recidivant mucosal melanoma in nasal cavity: Case report
    Levakov, A. Fejsa
    Kacanski, M. Mocko
    Amidzic, J.
    Sabo, J. Ilic
    Hardi, L. Vuckovic
    Vuckovic, N.
    VIRCHOWS ARCHIV, 2015, 467 : S81 - S82
  • [9] Primary mucosal melanoma of the nasal cavity, report of 5 cases
    Lajmi, Z.
    Tlili, T.
    Mabrouk, S.
    Fejji, Y.
    Sriha, B.
    Mokni, M.
    VIRCHOWS ARCHIV, 2022, 481 (SUPPL 1) : S290 - S291
  • [10] Malignant Mucosal Melanoma in the Nasal Cavity: An Uncommon Cause of Epistaxis
    Lo, Ru-Hsiao
    Chang, Kuo Ping
    Chu, Sau-Tung
    JOURNAL OF THE CHINESE MEDICAL ASSOCIATION, 2010, 73 (09) : 496 - 498