Iridium/Chiral Diene-Catalyzed Asymmetric 1,6-Addition of Arylboroxines to α,β,γ,δ-Unsaturated Carbonyl Compounds

被引：116

作者：

Nishimura, Takahiro ^{[1
]}

Yasuhara, Yuichi ^{[1
]}

Sawano, Takahiro ^{[1
]}

Hayashi, Tamio ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Sci, Dept Chem, Kyoto 6068502, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2010年 / 132卷 / 23期

关键词：

GRIGNARD-REAGENTS; CONJUGATE ADDITION; 1,6-CONJUGATE ADDITION; BORONIC ACIDS; LIGANDS; ARYL; 1,4-ADDITION; CURCUMENE;

D O I：

10.1021/ja1034842

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Iridium-catalyzed asymmetric 1,6-addition of arylboroxines to alpha,beta,gamma,delta-unsaturated carbonyl compounds to give delta-arylated carbonyl compounds in high yields with 90-99% enantioselectivity was realized by use of an iridium/chiral diene complex.

引用

页码：7872 / +

页数：3

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