Primordial germ-cell development: The zebrafish perspective

被引：207
|
作者：
Raz, E [1 ]
机构：
[1] Max Planck Inst Biophys Chem, D-37070 Gottingen, Germany
来源：
NATURE REVIEWS GENETICS | 2003年 / 4卷 / 09期
关键词：
D O I：
10.1038/nrg1154
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Primordial germ cells follow a characteristic developmental path that is manifested in the specialized regulation of basic cell functions and behaviour. Recent studies in zebrafish have greatly enhanced our understanding of the mode of specification of primordial germ cells, cell-fate maintenance and the migration of these cells towards their target, the gonad, where they differentiate into gametes.
引用
收藏
页码：690 / 700
页数：11
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