Arylation of α-pivaloxyl ketones with arylboronic reagents via Ni-catalyzed sp3 C-O activation

被引：36
|
作者：
Huang, Kun [1 ,2 ,3 ]
Li, Gang [4 ]
Huang, Wei-Ping [1 ,2 ,3 ]
Yu, Da-Gang [1 ,2 ,3 ]
Shi, Zhang-Jie [1 ,2 ,3 ,5 ]
机构：
[1] Peking Univ, BNLMS, Beijing 100871, Peoples R China
[2] Peking Univ, Key Lab Bioorgan Chem & Mol Engn, Coll Chem, Minist Educ, Beijing 100871, Peoples R China
[3] Peking Univ, Green Chem Ctr, Beijing 100871, Peoples R China
[4] Nanyang Normal Univ, Dept Chem, Nanyang, Hunan, Peoples R China
[5] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 25期
关键词：
CROSS-COUPLING REACTIONS; GRIGNARD-REAGENTS; ALKYL-HALIDES; NICKEL; ACIDS; ESTERS; AMIDES; PHENYLATION; ORGANOZINC; DISCOVERY;
D O I：
10.1039/c1cc11193k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A Suzuki-Miyaura coupling of alpha-pivaloxyl ketones via Ni-catalyzed sp(3) C-O activation to produce alpha-aryl ketones is developed. This study offers a convenient method to construct alpha-arylation products from readily available alpha-hydroxyl carbonyl compounds.
引用
收藏
页码：7224 / 7226
页数：3
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