A Randomized Crossover Study Evaluating the Use and Acceptability of the SILCS Diaphragm Compared to Vaginal Applicators for Vaginal Gel Delivery

被引：11

作者：

Beksinska, Mags ^{[1
]}

Greener, Ross ^{[1
]}

Smit, Jenni ^{[1
]}

Maphumulo, Busi ^{[1
]}

Mphili, Nonhlanhla ^{[1
]}

Kilbourne-Brook, Maggie ^{[2
]}

Coffey, Patricia S. ^{[2
]}

机构：

[1] Univ Witwatersrand, Dept Obstet & Gynaecol, MatCH Res Unit, Maternal Adolescent & Child Hlth Res Unit,Fac Hlt, ZA-3629 Durban, South Africa

[2] PATH, POB 900922, Seattle, WA 98119 USA

来源：

AIDS AND BEHAVIOR | 2018年 / 22卷 / 01期

关键词：

Diaphragm; Barrier methods; Gel; Multipurpose technology; MPT; Vaginal applicator; MICROBICIDE DELIVERY; PREVENTION; AFRICA; FEASIBILITY; ZIMBABWE; COUPLES; WOMEN;

D O I：

10.1007/s10461-017-1913-4

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

This study aimed to assess acceptability and preferences for the SILCS diaphragm for vaginal gel delivery compared to a prefilled applicator. A randomized crossover study among 115 women in South Africa, using both methods during five sex acts. We found no significant differences in acceptability between the two products. Experience of gel leakage after sex was greater when inserted via applicator. More women were interested in SILCS/gel for multipurpose protection (68%) than in either SILCS alone (17%) or microbicide gel alone (14%). A SILCS gel delivery system for multipurpose prevention seems feasible and acceptable.

引用

页码：127 / 132

页数：6

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