Mismatch repair status in sporadic colorectal cancer: Immunohistochemistry and microsatellite instability analyses

被引:40
|
作者
Yoon, Yong Sik [1 ,5 ]
Yu, Chang Sik [1 ]
Kim, Tae Won [2 ,5 ]
Kim, Jong Hoon [3 ]
Jang, Se Jin [4 ,5 ]
Cho, Dong Hyung [5 ,6 ]
Roh, Seon Ae [1 ,5 ]
Kim, Jin Cheon [1 ,5 ]
机构
[1] Univ Ulsan, Coll Med, Dept Surg, Seoul 138736, South Korea
[2] Univ Ulsan, Coll Med, Dept Internal Med, Seoul 138736, South Korea
[3] Univ Ulsan, Coll Med, Dept Radiat Oncol, Seoul 138736, South Korea
[4] Univ Ulsan, Coll Med, Dept Pathol, Seoul 138736, South Korea
[5] Univ Ulsan, Coll Med, Inst Innovat Canc Res, Seoul 138736, South Korea
[6] Kyung Hee Univ, Grad Sch EW Med Sci, Gyeoggi Do, South Korea
关键词
colorectal adenocarcinoma; immunohistochemistry; microsatellite instability; mismatch repair; prognosis; ADJUVANT CHEMOTHERAPY; COLON-CANCER; STAGE-II; GENETIC ALTERATIONS; 5-FLUOROURACIL; PATHWAYS; EFFICACY; UTILITY; METAANALYSIS; PROGNOSIS;
D O I
10.1111/j.1440-1746.2011.06784.x
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background and Aim: The aim of the present study was to evaluate associations between mismatch repair (MMR) status and clinicopathological characteristics and prognosis using immunohistochemistry (IHC) and microsatellite instability (MSI) analyses in a prospective cohort of a large number of accumulated samples.
引用
收藏
页码:1733 / 1739
页数:7
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