Generation of Singlet Oxygen during Photosensitized One-Electron Oxidation of DNA

被引：14
|
作者：
Osakada, Yasuko [1 ]
Kawai, Kiyohiko [1 ]
Tachikawa, Takashi [1 ]
Fujitsuka, Mamoru [1 ]
Tainaka, Kazuki [1 ]
Tero-Kubota, Shozo [2 ]
Majima, Tetsuro [1 ]
机构：
[1] Osaka Univ, Inst Sci & Ind Res SANKEN, Osaka 5670047, Japan
[2] Tohoku Univ, Business Dev Div Cooperat Res & Dev, Aoba Ku, Sendai, Miyagi 9808579, Japan
来源：
CHEMISTRY-A EUROPEAN JOURNAL | 2012年 / 18卷 / 04期
关键词：
charge transfer; DNA; DNA oxidation; photochemistry; singlet oxygen; GUANINE OXIDATION; MOLECULAR-OXYGEN; DAMAGE; MECHANISMS; PHOTONUCLEASES; PHOTOCLEAVAGE; STABILITY; MOIETY; BASES;
D O I：
10.1002/chem.201101964
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Crosstalk! It is demonstrated that singlet oxygen molecules ( 1O 2) are produced during the reaction between superoxide and the guanine radical cation; this suggests that the parallel typea I and typea II mechanisms intersect with each other during photosensitized DNA oxidation (see figure). Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：1060 / 1063
页数：4
相关论文
共 50 条
  • [1] Photosensitized one-electron oxidation of DNA
    Kawai, K
    Majima, T
    PURE AND APPLIED CHEMISTRY, 2005, 77 (06) : 963 - 975
  • [2] Modification of DNA bases by photosensitized one-electron oxidation
    Douki, T
    Cadet, J
    INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 1999, 75 (05) : 571 - 581
  • [3] CHEMISTRY OF SINGLET OXYGEN .37. ONE-ELECTRON OXIDATION OF TETRAMETHYLPHENYLENEDIAMINE BY SINGLET OXYGEN
    MANRING, LE
    FOOTE, CS
    JOURNAL OF PHYSICAL CHEMISTRY, 1982, 86 (08): : 1257 - 1259
  • [4] Effects of interaction of photosensitizer with DNA and stacked G bases on photosensitized one-electron oxidation of DNA
    Takada, T
    Kawai, K
    Tojo, S
    Majima, T
    JOURNAL OF PHYSICAL CHEMISTRY B, 2004, 108 (02): : 761 - 766
  • [5] Photosensitized generation of singlet oxygen
    Schmidt, Reinhard
    PHOTOCHEMISTRY AND PHOTOBIOLOGY, 2006, 82 (05) : 1161 - 1177
  • [6] THE CHEMISTRY OF YLIDIONS - PHOTOSENSITIZED ONE-ELECTRON OXIDATION OF PHENACYLSULFONIUM YLIDES
    ZHANG, JJ
    SCHUSTER, GB
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1989, 197 : 249 - ORGN
  • [7] Dynamic study of photosensitized one-electron oxidation of polyG by menadione
    Ma, JH
    Lin, WZ
    Du, FQ
    Han, ZH
    Yao, SD
    Lin, NY
    SCIENCE IN CHINA SERIES B-CHEMISTRY, 2005, 48 (04): : 292 - 296
  • [8] Dynamic study of photosensitized one-electron oxidation of polyG by menadione
    Jianhua Ma
    Weizhen Lin
    Fuqiang Du
    Zhenhui Han
    Side Yao
    Nianyun Lin
    Science in China Series B: Chemistry, 2005, 48 : 292 - 296
  • [9] Dynamic study of photosensitized one-electron oxidation of polyG by menadione
    MA Jianhua1
    2.Laboratory of Nanobiomedicine & Laboratory of Radiation Chemistry
    Science in China(Series B:Chemistry), 2005, (04) : 292 - 296
  • [10] Oxidation of guanosine via singlet oxygen vs. one-electron mechanisms.
    Burrows, CJ
    Muller, JG
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2003, 226 : U318 - U318
12345