TNF-α inhibition for potential therapeutic modulation of SARS coronavirus infection

被引：45

作者：

Tobinick, E ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Neurol Res Inst, Los Angeles, CA 90095 USA

来源：

CURRENT MEDICAL RESEARCH AND OPINION | 2004年 / 20卷 / 01期

关键词：

coronavirus; etanercept; H5N1; SARS; TNF;

D O I：

10.1185/030079903125002757

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Clinical and experimental evidence implicate TNF as a possible mediator of the severe immune-based pulmonary injury which can follow infection with H5N1 influenza and SARS coronavirus. Compared with the use of corticosteroids, the use of biologic TNF inhibitors, including etanercept, has the potential to be a more specific and more effective method of ameliorating the severe alveolar damage which can occur following infection with these agents. Further study is indicated.

引用

页码：39 / 40

页数：2

共 50 条

[1] Therapeutic Potential of TNF-α Inhibition for Alzheimer's Disease Prevention
Torres-Acosta, Noel
O'Keefe, James H.
O'Keefe, Evan L.
Isaacson, Richard
Small, Gary
JOURNAL OF ALZHEIMERS DISEASE, 2020, 78 (02) : 619 - 626
[2] The therapeutic potential of TNF-α blockade in rheumatoid arthritis
Paleolog, E
EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2003, 12 (07) : 1087 - 1095
[3] Improvement of potential therapeutic value of tumor necrosis-α (TNF-α) by charge modulation in the tip region
Fonda, I
Pernus, M
Gaberc-Porekar, V
Kenig, M
Stalc, A
Meager, A
Menart, V
EUROPEAN CYTOKINE NETWORK, 2005, 16 (01) : 17 - 26
[4] Metabolic alterations upon SARS-CoV-2 infection and potential therapeutic targets against coronavirus infection
Peiran Chen
Mandi Wu
Yaqing He
Binghua Jiang
Ming-Liang He
Signal Transduction and Targeted Therapy, 8
[5] Metabolic alterations upon SARS-CoV-2 infection and potential therapeutic targets against coronavirus infection
Chen, Peiran
Wu, Mandi
He, Yaqing
Jiang, Binghua
He, Ming-Liang
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 8 (01)
[6] The therapeutic potential of TNF-α antagonists for skin psoriasis comorbidities
Pierard, Gerald E.
Pierard-Franchimont, Claudine
Szepetiuk, Gregory
Paquet, Philippe
Quatresooz, Pascale
EXPERT OPINION ON BIOLOGICAL THERAPY, 2010, 10 (08) : 1197 - 1208
[7] The effect of inhibition of PP1 and TNFα signaling on pathogenesis of SARS coronavirus
McDermott, Jason E.
Mitchell, Hugh D.
Gralinski, Lisa E.
Eisfeld, Amie J.
Josset, Laurence
Bankhead, Armand, III
Neumann, Gabriele
Tilton, Susan C.
Schafer, Alexandra
Li, Chengjun
Fan, Shufang
McWeeney, Shannon
Baric, Ralph S.
Katze, Michael G.
Waters, Katrina M.
BMC SYSTEMS BIOLOGY, 2016, 10
[8] Therapeutic potential of ADAM17 modulation in gastric cancer through regulation of the EGFR and TNF-α signalling pathways
Sun, Jinbing
Jiang, Jianlong
Lu, Kuangyi
Chen, Qiao
Tao, Danhao
Chen, Zhong
MOLECULAR AND CELLULAR BIOCHEMISTRY, 2017, 426 (1-2) : 17 - 26
[9] Therapeutic potential of ADAM17 modulation in gastric cancer through regulation of the EGFR and TNF-α signalling pathways
Jinbing Sun
Jianlong Jiang
Kuangyi Lu
Qiao Chen
Danhao Tao
Zhong Chen
Molecular and Cellular Biochemistry, 2017, 426 : 17 - 26
[10] Inhibition of SARS coronavirus infection in vitro with clinically approved antiviral drugs
Tan, ELC
Ooi, EE
Lin, CY
Tan, HC
Ling, AE
Lim, B
Stanton, LW
EMERGING INFECTIOUS DISEASES, 2004, 10 (04) : 581 - 586

← 1 2 3 4 5 →