n-3 Polyunsaturated fatty acids and mast cell activation

被引：12

作者：

Wang, Xiaofeng ^{[1
]}

Kulka, Marianna ^{[2
,3
]}

机构：

[1] Univ Alberta, Dept Agr Food & Nutr Sci, Edmonton, AB, Canada

[2] Univ Alberta, Dept Med Microbiol & Immunol, Edmonton, AB, Canada

[3] Natl Res Council Canada, Natl Inst Nanotechnol, Edmonton, AB T6G 2M9, Canada

来源：

JOURNAL OF LEUKOCYTE BIOLOGY | 2015年 / 97卷 / 05期

关键词：

EPA; DHA; Fc epsilon RI; lipid rafts; eicosanoid; FC-EPSILON-RI; VASCULAR SMOOTH-MUSCLE; NERVE GROWTH-FACTOR; RECEPTOR CROSS-LINKING; LPS-INDUCED PRODUCTION; AFFINITY IGE RECEPTOR; GAMMA-LINOLENIC ACID; MAJOR BASIC-PROTEIN; EICOSAPENTAENOIC ACID; AIRWAY HYPERRESPONSIVENESS;

D O I：

10.1189/jlb.2RU0814-388R

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Mast cells are known to play a vital role in the development of inflammation in allergic responses. Recent studies have indicated that mast cell activation could be modulated by n-3 PUFAs, which have a wide range of well-documented health benefits. In our review, we summarize the recent findings and potential mechanisms of the effect of n-3 PUFAs on mast cell activation. This knowledge could provide new strategies for the development of therapeutic interventions for diseases mediated by mast cells.

引用

页码：859 / 871

页数：13

共 50 条

[1] n-3 Polyunsaturated fatty acids inhibit Fc ε receptor I-mediated mast cell activation
Wang, Xiaofeng
Ma, David W. L.
Kang, Jing X.
Kulka, Marianna
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2015, 26 (12): : 1580 - 1588
[2] N-3 polyunsaturated fatty acids and immune cell function
Calder, PC
ADVANCES IN ENZYME REGULATION, VOL 37, 1997, 37 : 197 - 237
[3] n-3 polyunsaturated fatty acids (PUFAs) inhibit mast cell activation by disrupting FcεRI association with lipid rafts
Wang, Xiaofeng
Kulka, Marianna
JOURNAL OF IMMUNOLOGY, 2014, 192
[4] The biochemistry of n-3 polyunsaturated fatty acids
Jump, DB
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (11) : 8755 - 8758
[5] Immunomodulation by n-3 polyunsaturated fatty acids
Netea, MG
Kullberg, BJ
Blok, WL
Van der Meer, JWM
IMMUNOLOGY TODAY, 1999, 20 (02): : 103 - 103
[6] Dietary n-3 polyunsaturated fatty acids modulate purified T cell subset activation
Arrington, JL
Switzer, KC
Fan, YY
Morris, JS
McMurray, DN
Chapkin, RS
FASEB JOURNAL, 2001, 15 (04): : A645 - A645
[7] Long-Chain n-3 Polyunsaturated Fatty Acids Inhibit Fcε Receptor I-Mediated Mast Cell Activation
Kulka, Marianna
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2015, 135 (02) : AB64 - AB64
[8] n-3 polyunsaturated fatty acids and immune function
Wu, DY
Meydani, SN
PROCEEDINGS OF THE NUTRITION SOCIETY, 1998, 57 (04) : 503 - 509
[9] N-3 polyunsaturated fatty acids and cardiac mortality
Singleton, CB
Walker, BD
Campbell, TJ
AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 2000, 30 (02): : 246 - 251
[10] n-3 polyunsaturated fatty acids and cardiovascular diseases
Nordoy, A
Marchioli, R
Arnesen, H
Videbæk, J
LIPIDS, 2001, 36 : S127 - S129

← 1 2 3 4 5 →