Potential mechanisms of adverse pulmonary and cardiovascular effects of particulate air pollution (PM10)

被引：118

作者：

Donaldson, K

MacNee, W

机构：

[1] Napier Univ, Sch Life Sci, Biomed Res Grp, Edinburgh EH10 5DT, Midlothian, Scotland

[2] Univ Edinburgh, Sch Med, Edinburgh Lung & Environm Grp Initiat, Colt Res Labs, Edinburgh, Midlothian, Scotland

来源：

INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH | 2001年 / 203卷 / 5-6期

关键词：

PM10; air pollution; ultrafine particles; transition metals; endotoxin; cardiovascular;

D O I：

10.1078/1438-4639-00059

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

PM10 is the international convention for measuring environmental particulate air pollution. Increases in PM10 have been linked to exacerbations of airways disease and deaths from respiratory and cardiovascular causes. PM10 is a complex and variable mixture but toxicological data suggests that ultrafine particles, transition metals and endotoxins are the most likely components to mediate adverse health effects. Potential mechanisms for the local and systemic adverse effects of PM10 are discussed.

引用

页码：411 / 415

页数：5

共 27 条

[1] Increased inflammation and intracellular calcium caused by ultrafine carbon black is independent of transition metals or other soluble components [J].